ID A0A063Y9Y4_9GAMM Unreviewed; 635 AA.
AC A0A063Y9Y4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase {ECO:0000313|EMBL:KDE41147.1};
DE EC=4.2.1.- {ECO:0000313|EMBL:KDE41147.1};
GN ORFNames=ADINL_0220 {ECO:0000313|EMBL:KDE41147.1};
OS Nitrincola lacisaponensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Nitrincola.
OX NCBI_TaxID=267850 {ECO:0000313|EMBL:KDE41147.1, ECO:0000313|Proteomes:UP000027318};
RN [1] {ECO:0000313|EMBL:KDE41147.1, ECO:0000313|Proteomes:UP000027318}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4CA {ECO:0000313|EMBL:KDE41147.1,
RC ECO:0000313|Proteomes:UP000027318};
RX PubMed=16280482; DOI=10.1099/ijs.0.63647-0;
RA Dimitriu P.A., Shukla S.K., Conradt J., Marquez M.C., Ventosa A.,
RA Maglia A., Peyton B.M., Pinkart H.C., Mormile M.R.;
RT "Nitrincola lacisaponensis gen. nov., sp. nov., a novel alkaliphilic
RT bacterium isolated from an alkaline, saline lake.";
RL Int. J. Syst. Evol. Microbiol. 55:2273-2278(2005).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDE41147.1}.
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DR EMBL; JMSZ01000007; KDE41147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A063Y9Y4; -.
DR STRING; 267850.ADINL_0220; -.
DR PATRIC; fig|267850.7.peg.216; -.
DR Proteomes; UP000027318; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:KDE41147.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027318};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 293..579
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 635 AA; 70258 MW; 49764F7B7B5AA69B CRC64;
MKQVMKRARL HVKLMTLHRS YKRLLMVAAD AVALPLALWS AYTLRFADPW PEFYLYPAAW
LFVILPVVGI LVFIKLGLYR AVVRYMGAQA IWTVAFGVLI LSLLLWAAAF VLQIKPFPRS
IPINFALVAM VYVGGSRLLM RSYYHWLLNH FLNKDSVLIY GAGGSGVQLA KALDGSQELS
CVGFLDDDPS LWRSSVAGFT VYDPSRIAEL IEEQQITSVL LAMPSAPPRV RKRILDRLAD
YPVHVRTIPA MHEIVSGVSV ASLREIEIED LLGRDPVPPI QPLIDASIRD KVVLVTGAGG
SIGSEICKQV QQHQPRLLLL YEQSEFALYS IEQTLSAFGA ECIPILGSVC DRQRVDDVLQ
RFAVQTIYHA AAYKHVPLVE HNVLEGVRNN ALGTQVMAEA ALQHGVERFV LVSTDKAVRP
TNVMGATKRL AELILQNLAS QSPKTIFSMV RFGNVLGSSG SVVPLFRKQI ESGGPVTVTH
PDITRYFMTI PEAASLVIQA GSMAKGGDVF VLDMGESVRI VDLARRMIRL MGYEVLDDKH
PDGDIEITFS GLRPGEKLYE ELLIGDDVIG TEHPKIMRAL EETLPPEVLS QILVGLNTAL
QQRNCVDARQ LLQQAVSGFK PTAKIVDWLA VEQVK
//
