ID A0A066RHM0_9GAMM Unreviewed; 656 AA.
AC A0A066RHM0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN ORFNames=EA58_20365 {ECO:0000313|EMBL:KDM89809.1};
OS Photobacterium galatheae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=1654360 {ECO:0000313|EMBL:KDM89809.1, ECO:0000313|Proteomes:UP000027192};
RN [1] {ECO:0000313|EMBL:KDM89809.1, ECO:0000313|Proteomes:UP000027192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S2753 {ECO:0000313|EMBL:KDM89809.1,
RC ECO:0000313|Proteomes:UP000027192};
RA Machado H.R., Gram L.;
RT "Draft genome sequence of Photobacterium halotolerans S2753: a solonamide,
RT ngercheumicin and holomycin producer.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDM89809.1}.
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DR EMBL; JMIB01000043; KDM89809.1; -; Genomic_DNA.
DR RefSeq; WP_036756818.1; NZ_JMIB01000043.1.
DR AlphaFoldDB; A0A066RHM0; -.
DR STRING; 1654360.EA58_20365; -.
DR OrthoDB; 9760224at2; -.
DR Proteomes; UP000027192; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.30.1120.80; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 283..552
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 330
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 291
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 448
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 502
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 503
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 656 AA; 73513 MW; D60F012F09769FBD CRC64;
MQKLKQKTGL LFPVILFSLM SLVFLSLSRV LLTAWQAEHV TGWQDWMMIL VQGVRIDIST
LCWLLLLPSL LLTLLPVQGI VGKFWLFLLR VWLVAGLWVL VYMELATPTF ITEYNLRPNR
LFLEYLIYPK EVFSMLWVGY KLELAIGLLG TLLTLFLGWK LSGYAVRDLN APKWFWRPVL
AVVVIVVGVM GARSTLQHRP LNPAMVAFST DPLLNDLTLN SAYSVIFAAK NMGSEKNAEE
FYGKMPLDEV VEMVRQASGR PDSFISDDIP TLNTNLPTFE GKKNLVILLQ ESLGARFVGA
LGGLPLTPNL DQLMQEGWNL TQVYATGTRS VRGIEAMTTG FTPTPSRAVV KLSKSQTGFY
TIAELLARQG YHTQFIYGGE SHFDNMKSFF LGNGFEEIVD LPDFENPKFV GSWGASDQDL
YQMADQQFTR LHNTGQPFFS LVFTSSNHSP YEFPDGEIEL YEQPEHSRNN AVKYSDKALG
EFFAKAKQSE YWKDTIFIVI ADHDARAEGK VPVPVDRFHI PAVILGGDVQ PRQDDRLASN
IDMAPTLLSL IGAENTSPMI GHDLTKDVAP EYQRAMMQFD KNFGYLTKDK LVVLQPGKAP
IGYHYDFGAQ SMTPASVNEA ESKRALAHAL LGGKLYRQGS YKLPLATEQQ LASADQ
//
