ID A0A066X1U6_COLSU Unreviewed; 993 AA.
AC A0A066X1U6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DUF221 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CSUB01_08486 {ECO:0000313|EMBL:KDN62942.1};
OS Colletotrichum sublineola (Sorghum anthracnose fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=1173701 {ECO:0000313|EMBL:KDN62942.1, ECO:0000313|Proteomes:UP000027238};
RN [1] {ECO:0000313|Proteomes:UP000027238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TX430BB {ECO:0000313|Proteomes:UP000027238};
RX PubMed=24926053; DOI=10.1128/genomeA.00540-14;
RA Baroncelli R., Sanz-Martin J.M., Rech G.E., Sukno S.A., Thon M.R.;
RT "Draft genome sequence of Colletotrichum sublineola, a destructive pathogen
RT of cultivated sorghum.";
RL Genome Announc. 2:E0054014-E0054014(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDN62942.1}.
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DR EMBL; JMSE01001284; KDN62942.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A066X1U6; -.
DR eggNOG; KOG1134; Eukaryota.
DR HOGENOM; CLU_009187_1_0_1; -.
DR OMA; GKGFFAW; -.
DR OrthoDB; 1330110at2759; -.
DR Proteomes; UP000027238; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF154; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027238};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 26..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 589..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..173
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 197..366
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 377..660
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 838..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 940..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..921
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 993 AA; 111968 MW; 8AF4B2921C33E821 CRC64;
MSVDAGKQLL DLIKNPYSQQ LQKNSIWAAL GTSLGVTVGI ALTFSLLRPY NQSVYAPKLK
HADEKHAPPP IGKKLWSWIP PLWKTTEDDM VHHAGMDATI FLLFIRMCLY MFLTISVFCL
AILIPTYMAN RTEGIDETWL DAITPIAVWG EAYWAQVAVA YMITFTVMGF LWWNYRKVML
LRRKYFESEE YQNSLHARTL MMYDIPKARC SDEGIARLID EVVPASSFSR TAIARNVKDL
PKLIEQHDHT VRKLEQVLAK YMKKPDQLPA ARPMCKPSKK DPSFATYPKG QKVDAIEYLT
QRIKELELEI REVRLSVDKR STMPYGFASY SDIAEAHNIA YACRKKRPHG AVITLAPRPN
DIIWDNLPLS ASVRRWRRIV NNLWIALLTF VWVAPNAMIA IFLINLDNLG NVWPAFQREL
ARDPNWWAIV QGIASPAITS LVYLVLPIIF RRLSMKAGDQ TKTGRERHVM AKLYAFFVFN
NLIVFSLFSA VWSFVSAVVS ETNDKRTDAW HAIIDQNLAT TLFTALCKVS PFWVTWLLQR
NLGAAIDLAQ LWTLVYSFFV RKFSSPTPRE LIELTAPPSF EYAMYYNYFL YYATVALGFS
GIQPLVLPAA TLYYAIDYWL KKYLLLYIFV TKNESGGMFW RVLVNRMLFA VFLSNCVFFL
SAWARSDWAT HKQALAIAPL PILLIIFKIV CVRVFDDKIH YLSTTNVAKH PEAGMQKETR
LRSERLASRF GHPALYKPLI TPMVHQKAQP YLHIVYKGRL SDGREANSGD MMSVSGYSDT
YAMDPMSSGK PGKSANVPGF EFVSESNLDF EFYKNRAEFA DEHGNGDLFG QDPDIMRPGT
PGSMSDYGSR PGTPTAVQLQ GGMTGQRRDI SAQSGSSSYK PNPPGYMSPT ANGQQSPTRL
GSPQAGFAQQ ATMGDRSRSP LYHINSNESD RALVRNAAGM PISPPAAGPT VGALGGGPRG
YSGLPQADAE TLDQDPSTYD YFRGSRRRPN DGW
//
