ID A0A066X7N8_COLSU Unreviewed; 646 AA.
AC A0A066X7N8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300};
GN ORFNames=CSUB01_04003 {ECO:0000313|EMBL:KDN64977.1};
OS Colletotrichum sublineola (Sorghum anthracnose fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=1173701 {ECO:0000313|EMBL:KDN64977.1, ECO:0000313|Proteomes:UP000027238};
RN [1] {ECO:0000313|Proteomes:UP000027238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TX430BB {ECO:0000313|Proteomes:UP000027238};
RX PubMed=24926053; DOI=10.1128/genomeA.00540-14;
RA Baroncelli R., Sanz-Martin J.M., Rech G.E., Sukno S.A., Thon M.R.;
RT "Draft genome sequence of Colletotrichum sublineola, a destructive pathogen
RT of cultivated sorghum.";
RL Genome Announc. 2:E0054014-E0054014(2014).
CC -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also
CC known as the alpha DNA polymerase-primase complex) which plays an
CC essential role in the initiation of DNA synthesis.
CC {ECO:0000256|PIRNR:PIRNR018300}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR018300}.
CC -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDN64977.1}.
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DR EMBL; JMSE01001078; KDN64977.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A066X7N8; -.
DR STRING; 1173701.A0A066X7N8; -.
DR eggNOG; KOG1625; Eukaryota.
DR HOGENOM; CLU_014923_1_0_1; -.
DR OMA; PFLDIEH; -.
DR OrthoDB; 49016at2759; -.
DR Proteomes; UP000027238; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.60.21.60; -; 2.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016722; DNA_pol_alpha_bsu.
DR InterPro; IPR013627; Pol_alpha_B_N.
DR PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
DR Pfam; PF08418; Pol_alpha_B_N; 1.
DR PIRSF; PIRSF018300; DNA_pol_alph_2; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000027238}.
FT DOMAIN 19..242
FT /note="DNA polymerase alpha subunit B N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08418"
FT DOMAIN 355..590
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT REGION 77..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 646 AA; 71360 MW; 54C288DF86611784 CRC64;
MAEVELREFF TTGDKSLEDD VLSELQSIMR LHELSAEDLF YKWESFCIKM DMDAMNPDIV
HVRNFKKDIQ DALEKSNRQQ THIKTEKRSH GTPRAGRGGD VFGMLDGLVP STPGPGKLNK
PSSVRKKANE TPTMSRVKAE IPSSSPDYKG PSSFNDRQNA GETIEVLNDH LEAPEPPICP
YSEPRIKLTA ASDQKKLAYK PLAMKLSEAS EILDDRIDEF MHIVQEHHKL DFSEFGNAAN
QSTTEVIAVG RIASDAPEGK LNAASLVLEM SRRTGGGLRV PLNMRNKSYS FFPGQIVALK
GINTSGNEFA VEEVLEVPLL PNAASTPAVL AAHREKLRGD PEAMDTDSDP APLNVVYASG
PYTADDNLDF EPLYALCDQA ADTYADALVM TGPFIDSEHP LIATGDFDLP DEVAIDPDTT
TMSTVFKYMF SPALNRLVSA NPSITILLVP SVRDVIDKHV SWPQDSVLKK ELGLPKTARI
VTNPMTLSMN EMVMGISSQD ILWQLRHEEL VGGRPSDPSL LSRLSRYLLE QRHFFPLFPP
TDRTKLPKTG TEEGIPPGAM LDLSYLKLGE MVNVRPDVLV VPSFLPPFAK VVESVLMINP
GYLSKRRGAG TYARLTLFPP KPNAGHSEAM VSHGVFERAR VEIKRI
//
