ID A0A066ZS77_HYDMR Unreviewed; 354 AA.
AC A0A066ZS77;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Hemolysin D {ECO:0008006|Google:ProtNLM};
GN ORFNames=EI16_08745 {ECO:0000313|EMBL:KDN96352.1};
OS Hydrogenovibrio marinus.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Hydrogenovibrio.
OX NCBI_TaxID=28885 {ECO:0000313|EMBL:KDN96352.1, ECO:0000313|Proteomes:UP000027341};
RN [1] {ECO:0000313|EMBL:KDN96352.1, ECO:0000313|Proteomes:UP000027341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MH-110 {ECO:0000313|EMBL:KDN96352.1,
RC ECO:0000313|Proteomes:UP000027341};
RA Cha H.J., Jo B.H., Hwang B.H.;
RT "Draft genome sequence of Hydrogenovibrio marinus MH-110, a model organism
RT for aerobic H2 metabolism.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- SIMILARITY: Belongs to the UPF0194 family.
CC {ECO:0000256|ARBA:ARBA00010602}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDN96352.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JMIU01000001; KDN96352.1; -; Genomic_DNA.
DR RefSeq; WP_051623113.1; NZ_JMIU01000001.1.
DR AlphaFoldDB; A0A066ZS77; -.
DR STRING; 28885.EI16_08745; -.
DR Proteomes; UP000027341; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR PANTHER; PTHR32347:SF23; UPF0194 MEMBRANE PROTEIN YBHG; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027341};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 5..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..323
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 33..292
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 326..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 77..130
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 174..201
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 354 AA; 39113 MW; 1D144CF5C8FCF0FD CRC64;
MKKRILILVV LLIIAGGIYW FASNSNSSEQ NGHIKLYGNV DIRQVNLAFQ VTGQIEKIDV
QEGASVTTGQ KLACVDKTRY EAQLDLAQEQ VNSLEAQLDK MLAGNRPEDI AQAKNRYLAA
KAEAEQAAKS YRRLKTLLPK KLASQDDVDI ASSKADATRH NEMAAENAWV VAKLGARKED
IAQVRAQIAQ AEAQVTLAQK NLTDSNLISP VDGIIRDRIL EPGDIAQPQQ TVMTLALQNP
KWIRAYVSEN QLGKVKIGLP ATITTDSYPN KVYHGWVGYL SPVAEFTPKT VQTEDLRTQL
VYQVRIYTCD TSGELRLGMP ATVTIDPRDK PLKEPTCSAN SVESSDEMND FESK
//
