ID A0A067BRA7_SAPPC Unreviewed; 690 AA.
AC A0A067BRA7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=SPX domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPRG_15396 {ECO:0000313|EMBL:KDO19335.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO19335.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO19335.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO19335.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR EMBL; KK583356; KDO19335.1; -; Genomic_DNA.
DR RefSeq; XP_012209955.1; XM_012354565.1.
DR AlphaFoldDB; A0A067BRA7; -.
DR EnsemblProtists; KDO19335; KDO19335; SPRG_15396.
DR GeneID; 24137130; -.
DR KEGG; spar:SPRG_15396; -.
DR VEuPathDB; FungiDB:SPRG_15396; -.
DR OMA; KKRGDNC; -.
DR OrthoDB; 103051at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14447; SPX; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 212..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 560..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 587..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..682
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..157
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 443..647
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
SQ SEQUENCE 690 AA; 80560 MW; A1D8962BD023C35C CRC64;
MSRFQDKLEA NTYREWKEHY IEYAALKLAV NGMREDVAGF DLEAQLDKVV ELQFLVGAAG
STVQSFEKLF IKEYSKVETF YVASIREFKL QLDTLLKQHH NNMTEATRQA MIAACMELYR
LLNMLVNFAM LNYTGLTKIL KSHEKKVRSQ ESIRYVFAEK IETCAFAQAT EARAEVLRLE
DWFTRTFHSG NRPVAISELM SRRVEIVDWA QAYMGVKFGC LLMLGLWVIW DAGIIPSIAT
NDNHLRLLLT KGFPLFRGMG CVILFNWLMG VSLYVWRSAR INYKYIMDLD PHKTKDYDQV
FHDAAHVSIV YLVCMLVYYK VCNDEFPESK VVHRGYVLLV LFLYMIYFYL IRDWKLKIGL
VKVVAEIFGA PWFPVTFLHT FIGNYMLSMQ RMNQDIAWSV CFFVTGEFLE TDDLQMLHAG
GTDMKGYLHN HTMQGIVPSK CYKNFYYAKV VVPLLCALPL WYRFLQSLRR IYDMKQWWPG
VGNVIKFGLT MIVVLFGLFH PFHNPVRPIE SISPLQQVWI AGFIIASFLL WFWDVTMDWG
LMRPEHKFLA ERHMYPRRTV YYIAIVADFF LCYAWVLTLI PPSAEQALNH SFFVYIHPFS
MVLEPIRRTI WSFFTVENEH LRNTMGFRKE QFVPLFFERG VGAPPPDDTS ETAQRLKRRT
KLLISGVIAF VLFLALAAMT IVEETTIPTN
//
