ID A0A067BX60_SAPPC Unreviewed; 916 AA.
AC A0A067BX60;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=AP-3 complex subunit delta {ECO:0000256|PIRNR:PIRNR037092};
GN ORFNames=SPRG_15843 {ECO:0000313|EMBL:KDO18891.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO18891.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO18891.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO18891.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBUNIT: Adaptor protein complex 3 (AP-3) is a heterotetramer.
CC {ECO:0000256|PIRNR:PIRNR037092}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000256|PIRNR:PIRNR037092}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|PIRNR:PIRNR037092}.
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DR EMBL; KK583386; KDO18891.1; -; Genomic_DNA.
DR RefSeq; XP_012210412.1; XM_012355022.1.
DR AlphaFoldDB; A0A067BX60; -.
DR STRING; 695850.A0A067BX60; -.
DR EnsemblProtists; KDO18891; KDO18891; SPRG_15843.
DR GeneID; 24137527; -.
DR KEGG; spar:SPRG_15843; -.
DR VEuPathDB; FungiDB:SPRG_15843; -.
DR OMA; SGNNWMA; -.
DR OrthoDB; 25313at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0030123; C:AP-3 adaptor complex; IEA:InterPro.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR017105; AP3_complex_dsu.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR PANTHER; PTHR22781:SF12; AP-3 COMPLEX SUBUNIT DELTA-1; 1.
DR PANTHER; PTHR22781; DELTA ADAPTIN-RELATED; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR PIRSF; PIRSF037092; AP3_complex_delta; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|PIRNR:PIRNR037092};
KW Protein transport {ECO:0000256|PIRNR:PIRNR037092};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transport {ECO:0000256|PIRNR:PIRNR037092}.
FT DOMAIN 23..577
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT REGION 669..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..838
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..853
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 854..899
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 916 AA; 101908 MW; 3BAC5DDF0F2ABEA7 CRC64;
MFEKTLADLV KGIRSCKGDV SVYISQCMQE IKNELKANDP FIKAQAIRKL TYLNMQGYDM
GWAAFHVVEV MSYERFAHKR IGYLAAGQSF TQATDVVLLC TNLFKKEFGS VNEFEVGLAL
NAMANICTTD LARDLLGDIL ALMNSHKPYV RKKATLILYK LFLRYPQGLR LSFDRLKERM
EEPDVGVVSC SVNVICELAN KKPKNYVGLA PQFFRLLTTS SNNWMLIKVV KLMSSLVPEE
PRLARKLLDP LATIIQNTPA KSLLYECIST VTTALLYTQK SDGSQPRNVP AIVKLCNDHL
RRYIEDPDQN LRYLGLVGLS NLMQSHPHVI SEHQQIILEC LSVEDTTIRL RSLELLAGMV
SPENAPAIIQ ELMRHTMVSD GVYRQELIVK ILHVCSLNKY HNVQDFEWYI RILCQLSKLP
GKEASSVHGA EITRQLMDIA VRVKGIRSVL VKYMMALLLD KAALQDAGAA TTAQVLYAAG
WIVGEYILDD DESDGEEARL EKMVDVVDVM LQPSTTSLPA NVQAVYMHNI LKLLMAAAEK
ADDATVELVA KMILERLPAF VQSEHIEVQE RACTLEHVVL GLGLGLDALS PEDRANRVFG
GAMITTSDGR LGVLNGFFNE PLAPVGAKAQ RKVPLPPGLD LDTPFAKEEA AFLVAGDADG
STTDDEVSFV HSSHAKEPDT GYVNLGATSS SDEETDGEDA KAILEKQYAM EQERLRQDPF
YIKPSHSAAP NDDMFGNILN ALDAKKSKSK KKSKTPKKQR AIVLDDVMPD GGDSSEDEGG
RRGRHGKRRS SKDVDLAEVD LTMPLRDDER IPDSHWQHRQ VLDRAPSMND DDDDGGKKKK
KKKTKKTKDE PKPKKSKKAK EVEMVLVEEE VKKPKKSKQK SGKEAKEDKP KKSSKKSSKK
AADGGGVLND EPLLMF
//
