ID A0A067BZK8_SAPPC Unreviewed; 610 AA.
AC A0A067BZK8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=TKL protein kinase {ECO:0000313|EMBL:KDO19726.1};
GN ORFNames=SPRG_14253 {ECO:0000313|EMBL:KDO19726.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO19726.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO19726.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO19726.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
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DR EMBL; KK583337; KDO19726.1; -; Genomic_DNA.
DR RefSeq; XP_012209585.1; XM_012354195.1.
DR AlphaFoldDB; A0A067BZK8; -.
DR STRING; 695850.A0A067BZK8; -.
DR EnsemblProtists; KDO19726; KDO19726; SPRG_14253.
DR GeneID; 24136068; -.
DR KEGG; spar:SPRG_14253; -.
DR VEuPathDB; FungiDB:SPRG_14253; -.
DR OMA; NIMRHAW; -.
DR OrthoDB; 49352at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13999; STKc_MAP3K-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR44329:SF214; ANKYRIN REPEAT-CONTAINING PROTEIN KINASE A-RELATED; 1.
DR PANTHER; PTHR44329; SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR00109; TYRKINASE.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:KDO19726.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transferase {ECO:0000313|EMBL:KDO19726.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 268..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 349..610
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 297..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 66141 MW; 199E3570F6C92BC6 CRC64;
MATTWLESAD LVAKIHAIKA ANVSDANMWN PETAPPSVAS RLAALSLNWA DLGNADKQAL
LWDMGLVRTT TAENNQVTQV YTKCSDSGGG DSMATIALSK AAFLQSQADA TVRTCTSSTI
NTTYVRQENS NGGKLAPYTK CMIANVTGVA DSHSSMWAQD GQGLSTYPVP NIMRHAWSAS
DSWLIYAIHT QTAGDEIGFG FCGPSSTPGG LTIPCQVFDG SGPPQGWCLP TPSARMTQSL
ARIALAKPST SMPAPTLAPT DGSSNHTVLI VCLVAGAILV ALGAWCCIRR RRKPTTTHGD
FTAYRSNPPR GATSSPPTSY QPITTASHTL NEFQRDPSLS QKRLPYSSVV CSRLLSKGAF
GEVWLGSFNG QVVAVKRLLD SKRTSEAEIE AFADEIRLMA SFTHPNIVRF VGFAWDSLQN
LCAVTEYMPQ GDLHTYLQSH LQLQWRRHEK IKIALGIAHA LAYLHSLSPA IIHRDLKSKN
VLMAAGCEAK LSDFGISRER TLDETMTAGV GTIFWTAPEV LLGEHYSEMA DIYSFGVVLC
EIDTREAPYP NMKAVPQVTM VHRITNEGLR PAFSEACPAQ LQTIASRCLD ADPTMRPSAR
ELVTILSEWR
//
