ID A0A067C0B6_SAPPC Unreviewed; 1645 AA.
AC A0A067C0B6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=SPRG_10680 {ECO:0000313|EMBL:KDO23983.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO23983.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO23983.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO23983.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
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DR EMBL; KK583247; KDO23983.1; -; Genomic_DNA.
DR RefSeq; XP_012205304.1; XM_012349914.1.
DR STRING; 695850.A0A067C0B6; -.
DR EnsemblProtists; KDO23983; KDO23983; SPRG_10680.
DR GeneID; 24132778; -.
DR KEGG; spar:SPRG_10680; -.
DR VEuPathDB; FungiDB:SPRG_10680; -.
DR OMA; KRMCQHR; -.
DR OrthoDB; 297674at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 4.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR031649; GPHH_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF62; SODIUM CHANNEL PROTEIN 60E; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF16905; GPHH; 1.
DR Pfam; PF00520; Ion_trans; 4.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 4.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 54..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 507..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..612
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..698
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 801..818
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 838..859
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 931..953
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1104..1125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1180..1201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1208..1228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1248..1275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1296..1321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1452..1487
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 716..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1612..1645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1645 AA; 184995 MW; 6B3079105B9BE053 CRC64;
MAPDRPVTPQ LPRAMRKLRE PRTVQRISLG CLNTKHPLRR VCIKILQSPW FDRVIILAVC
CNTVILGLVD YENAWVEGPN PNMGVNKLIE QWNGVSLYIF VAEMVVKIIA MGFFVGEGAY
LLDSWNRLDF VIVLSGMLSV LNIKVGFVRV LRVLRPLRTL HTFPGLKVLT NSLLSSLPAL
GNVAILLAFI YIVFAILGME IWRGAFHSRC RLTPFPIALP FDALNPPGAN AYPVSAAYLA
KVLANPAWYR CNKSDGSAYL VDDTWDIRAN CFWPLDSGLP MPRLCSSSGR TCNVNQTCGS
NYDPNGNPRF LDIAGPLLNL SIMGEPTFNA NLNFGLTNFD NLGNTLMVIL QVVTASGWMA
LTETAQWVGN PALAAIYFNL LLIIGMCFLL QLNMAVLFTE FEKAKDQQAK AAHARAVDVI
KRLSMVPPPP VSTSQTKRID TADVVVAPAW RRCVVEWRLC IRQVVLTTAF RRLGIFITLS
NVFVMSLNHT EMSYTFAYNC EVLNFTFMIY FGIESLLKMI ALDLRPFWAD KFNRFDLFTF
LIGIVEAMLN PPTFIDGTSG GSGLFTAFRV ARAFKLARSW KSLNKLLMAI LNSFGEILNF
LFFLVLFCYI YALLGIELFA TKFQFDVNNH ALPYNNTNPT SLRHRNNFDS ITWAFFTVFQ
VITYDNFPNV TYDGWISVGW ISPVYFASII VFGVWIVMNM FSAILVQSCM VDDEDDDDDK
GDDGNNGKRR TRRPANRRVR RAKRAMFQLI RFFDANVHDP NEARQREAAS YLLNKGNALL
LFSPRNPIRR FCVVLLQRRE WTWFISISIA VSCIFTAIDT PLLDPNSSLG QSIATSNAVF
AMLFTCELVI AVIAKGLFFG RGAYLKDPWR ILDGFIVSVS VLPYLIGNAK GTLSGLRALR
AFRAFRPLRV INKLPQLKIV VNTLFRCIPD ILNALVFFFF MLFIFGLMGI SLFKGALSTC
SISPYTYTQG TGTPAFPPWF PSGYAGDFVT NMTSIDTMTY PIAWSNMTAS QKAPYAAVWN
TTGCGPFADD YLPTSKQMCL CFAATHKTTW NSLVPQKFDN IFWAVAGLYE LTTMEAWSLT
ALAAVDSVGE DMQPILNNQP LVMIWWWLYM IVCAFFITNL FIGVLCDSFC RESYGAVVTE
EQIKWIKLQK KVLALSPQVT HPVPHGRFRE LSFHIVHWPW FEYIITACIL VNMICMAIQA
YGQSASFLLA LSVLNSIFTG IFTCEAILKL NAFGYAYFDE AWNRFDFTIV VFAMASIILP
LVTTSLSLGT VLTVVRVFRV GRALRLIKKA KLMKNLFDTL TVSLPAVGNV TSLLMLLFYI
YSAVGVQLFA KVAYNNQGIH QYQNFQNFFR ALQALIGFST GENWDNFTWE IYYTSPATNP
SCDDRTFNGN MCGFNDTDPY NCIPLDGCGS WFIVPFMYSM YLIIGYLGMN LFSGIVIDAI
GDSSAASPVN PATLAEFADR WAEFDPQGGG LITAEELADF LYTVYPPFGF KSVPGFTRRR
VVIAIGELDI PVYDKIYVHF KDVPRALVMR VLAEGSVTKY NEINKLMDQL GINKQFDELW
HRRRGKKQKD RLSMREVGRV KEYSATIMIQ RFVQRARAKR LRAKLAATDL STSDPDLAHE
SATVHGEPLM SVDAPETTEA STAIA
//
