ID   A0A067C822_SAPPC        Unreviewed;       286 AA.
AC   A0A067C822;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Glycosyl hydrolase family 30 TIM-barrel domain-containing protein {ECO:0000259|Pfam:PF02055};
GN   ORFNames=SPRG_11814 {ECO:0000313|EMBL:KDO22967.1};
OS   Saprolegnia parasitica (strain CBS 223.65).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO22967.1, ECO:0000313|Proteomes:UP000030745};
RN   [1] {ECO:0000313|EMBL:KDO22967.1, ECO:0000313|Proteomes:UP000030745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO22967.1,
RC   ECO:0000313|Proteomes:UP000030745};
RX   PubMed=23785293;
RA   Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA   van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA   Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA   Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA   Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA   Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA   Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA   Russ C., Tyler B.M., van West P.;
RT   "Distinctive expansion of potential virulence genes in the genome of the
RT   oomycete fish pathogen Saprolegnia parasitica.";
RL   PLoS Genet. 9:E1003272-E1003272(2013).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382}.
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DR   EMBL; KK583259; KDO22967.1; -; Genomic_DNA.
DR   RefSeq; XP_012206259.1; XM_012350869.1.
DR   AlphaFoldDB; A0A067C822; -.
DR   EnsemblProtists; KDO22967; KDO22967; SPRG_11814.
DR   GeneID; 24133828; -.
DR   KEGG; spar:SPRG_11814; -.
DR   VEuPathDB; FungiDB:SPRG_11814; -.
DR   OrthoDB; 3473901at2759; -.
DR   Proteomes; UP000030745; Unassembled WGS sequence.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          49..99
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
SQ   SEQUENCE   286 AA;  31191 MW;  4A945737F9C78ED4 CRC64;
     MRTSMMPRPP TLSMTHWYVM GAWELDGVMH HAELHSCTYP DVASGQRYNA HDILGNLNNW
     AVGWVDWNLL LDHNGGVNHL ANTCDAPLVL TPDETSFIHV SRFIPPGSTR IAAHVTCDAL
     LADYPRVSTP ATRASAKHGS AHTMTSFKTT APPITSRSAR LYLAPRRPSS TAPTRHRGRL
     SRGSIRSGEL CGSAGHASRN ISAVLSLEPC VSADHQAWSF QDGPPRDKLC VTAGYAFAQA
     AAFVTLSGFK VLVALNEHSE GALCLDDERR QTVVPKRGIR TYKWAS
//