ID A0A067C916_SAPPC Unreviewed; 538 AA.
AC A0A067C916;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Folate-Biopterin Transporter (FBT) Family {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPRG_08944 {ECO:0000313|EMBL:KDO25645.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO25645.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO25645.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO25645.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
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DR EMBL; KK583230; KDO25645.1; -; Genomic_DNA.
DR RefSeq; XP_012203676.1; XM_012348286.1.
DR AlphaFoldDB; A0A067C916; -.
DR STRING; 695850.A0A067C916; -.
DR EnsemblProtists; KDO25645; KDO25645; SPRG_08944.
DR GeneID; 24131144; -.
DR KEGG; spar:SPRG_08944; -.
DR VEuPathDB; FungiDB:SPRG_08944; -.
DR OMA; SIHMDIT; -.
DR OrthoDB; 50060at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF5; RIBOSOMAL_L9 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03092; BT1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 38..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 538 AA; 58369 MW; CA67F831924FB352 CRC64;
MEHEERAPFV ATTKSASYGH ASDLEAGLRV LSLRSPEAVA LFSQYVAIGI LYGLLPGLQY
PIFNNYLHME GYQTSAYGVL IHIGWSFKVF LGMLSDCVPI FGYRRKSWML LGWTIAIVSL
GFLTFTPFPS PYCDARYIAC PAVRPSPLVN ASFYNLDAPD AGTSIIVLSV LVGFGYVMAN
SAADAIVVEY TQREPLATRG RTQSAIYASR YAGQMLAQTA IALLLNGKVY GGSFDFDVPP
NVVYGLCLAP SVLILPSTLL CLVEHPSAPT PIPIWLHSFW QLLQVPAMWR VCAFKFLNSA
APIARTWAHV EPLNDAIAGV LGSLAMALIM AGVGRFGLHW NWRTVVAIST VGIIAIDAVA
VFATVWDLVR NQWFYNGVVL AEKVPDGIRF MVASYCAVEI ADVGNEGATY GLVTTLGNLA
SPFAAVFYKL ADATFDVSQD AIARDDVDVR WQVTYCFLLS YGVRLAGLFW LFLLPPQKAA
LRHLKQHGTP SAAAGATVVV VFVLALLLSV TTNFMSIYPA TKCYRIAGGH GTVNGTCV
//
