ID A0A067CB48_SAPPC Unreviewed; 782 AA.
AC A0A067CB48;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Heat shock 70 kDa protein {ECO:0000256|ARBA:ARBA00018181};
GN ORFNames=SPRG_10519 {ECO:0000313|EMBL:KDO23741.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO23741.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO23741.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO23741.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
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DR EMBL; KK583250; KDO23741.1; -; Genomic_DNA.
DR RefSeq; XP_012205559.1; XM_012350169.1.
DR AlphaFoldDB; A0A067CB48; -.
DR STRING; 695850.A0A067CB48; -.
DR EnsemblProtists; KDO23741; KDO23741; SPRG_10519.
DR GeneID; 24132627; -.
DR KEGG; spar:SPRG_10519; -.
DR VEuPathDB; FungiDB:SPRG_10519; -.
DR OMA; TRIYTTE; -.
DR OrthoDB; 50968at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR19375:SF395; HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 91..124
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT COILED 124..179
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 782 AA; 85803 MW; F46656463A23D93E CRC64;
MTGTSHFSDQ FAALSTEERK AAGAEAKNRG NAAYTAADFA TAIKEFTTAI AYEPHNHAYY
SNRSAAYLSN GNAAPAMADA NKCIEIDAKW GKGYARLGAA YYFIKSYEKA IQAYSKGLTV
DKGNKQLLAG LTQAQAALQV LQEEASGVEM DDATRKMKRM EIEDKINKAR AEREERAARA
ERGFSEVIGI DLGTTYSCVG VWKDGQVEII ANSEGNRTTP SWVAFNEAER LIGDAAKLQA
ASNATNTVFD AKRIIGRAFS DPIVKKDAAH FPFKIVEGEG DKPLIQVTFK GEEKNFSPEE
ISSMVLTRMK ETAENYLGQE IKQAVVTVPA YFNDQQRQST KDAGAIAGLD VKRIINEPTA
AALAYGLDTN AGADGSKTNI LIFDLGGGTF DVSILSIENG IFEVKSTGGD THLGGEDFDS
NMVDYLITEF KRKNKGLDPT SSARSMRRLR TACESAKRML STTTSASIEV DSLFEGVDFS
STMTRAKFES LNEECFKRTE ETVLKVLADA NMQPGDITEL VLVGGSTRIP KVQNMLSAVF
GGKELSKSIN PDEAVAYGAA VQGAILSGIR NDATNSLLLV DVTPLSLGIE LVGKVMSVLI
KRNTAIPVKK TRIYTTEEDW QTTEKVVIFE GERACVVDNN KLGEFEISGI ERAKRGEPQI
EVTFEIDANG ILHVSARDKK TGAKNATTIS NNRGRLTQQD IDRMVEEAEK FKKDDAQMLK
RIDARNDLEG YLYRALEAAS KKNDAAAQTA LREARDWMDD NEELTVRELE DKRRVLERTY
KY
//
