ID A0A067CH48_SAPPC Unreviewed; 1377 AA.
AC A0A067CH48;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Polymerase nucleotidyl transferase domain-containing protein {ECO:0000259|Pfam:PF01909};
GN ORFNames=SPRG_19699 {ECO:0000313|EMBL:KDO29813.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO29813.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO29813.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO29813.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
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DR EMBL; KK583204; KDO29813.1; -; Genomic_DNA.
DR RefSeq; XP_012199522.1; XM_012344132.1.
DR STRING; 695850.A0A067CH48; -.
DR EnsemblProtists; KDO29813; KDO29813; SPRG_19699.
DR GeneID; 24140993; -.
DR KEGG; spar:SPRG_19699; -.
DR VEuPathDB; FungiDB:SPRG_19699; -.
DR OMA; FPWHESA; -.
DR OrthoDB; 214700at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45979; PAP/OAS1 SUBSTRATE-BINDING DOMAIN SUPERFAMILY; 1.
DR PANTHER; PTHR45979:SF5; PAP_OAS1 SUBSTRATE-BINDING DOMAIN SUPERFAMILY; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF13432; TPR_16; 2.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 5.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 102..135
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 136..169
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 207..240
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 241..274
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 368..401
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 999..1035
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT REGION 585..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 900..927
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 605..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..684
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..732
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..852
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 853..886
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1377 AA; 151144 MW; C6243BE29A3CC374 CRC64;
MEGKQLQSAI LKYRNLNDRK SAPAAADGGQ AAAASAAKKR RPFTYTDHSD TIAQLLSGST
AASASSNNKL NSVYPTSTLL RSTAAAASYN ASTMASTDGF QYEEAFQRGM KLVEKNDYKR
ALSEFTEAIN VAPTKLKAYV QRAMCYMKAQ RYEPAIDDYS TLIAHTPGDS DMFSKRAFAY
ECHNKIPSAI EDYTKAIEIS GVPAKIKDAR LARGKAYAKL GHLTHALEDF GSVIEMDPRS
DDGYRQRGLV YTRLCKFDLA LADYDRVVEL EARQLTHVKL ESLLQRAETL MKLVETEENG
FLLHQMEDSA LLSAENGHDR AVRHTPRTIC LAMDETYLTP CESDDARSFA LKAIDDFTAA
LDQEPESLDV LAARGEAYIR AGALTKALAD FDAALLIDAK DHRLLLSRAV VLQLQDDAAR
PGHVSARALA LLAQVTSSAP PLIASQGFFR RARLYLEHGQ PQAAVDDLGK IVDLFPKVLN
EERDSGADYL PDEQVKPHCL VGATSKESKS PVRIALQALL SRARVHMQLQ SYALAAKDYQ
AILAVSPGHL DAQVEEQQAR DLDEKHKVEE SNRAVKWLLE HGDATEVTKK GARKKKKKTA
KASTTTDRHR RPPAIRVKDA VTTDDDDDES GDNAARPATN DDDDDDDDMV PTPDASIPPP
PVPQKISPTG SLGHRSSTPS SRMVMYTRDE ACESLYETEA PAERVVPPRP TFHFSLTDDV
PKDGDVTAKS SDDDETPMTT TTTKDDKSGA STPAASPVVL VDDKYLKKRR KQLEKLRADL
VDVCQRRERD LIVDALDRAT RKQMVDQLQD ECQRARDVLE ELKLHVEATP AQSPQRATPT
TSSDASPVRL PSSSPPSRSP GKPPVSGVPP PIKTAGSPPR PIVSSPARPP RQAAESPDDM
ARLRYQIDML QRALSEKQHE IDQLKRHAAL VPPVSSPLPL SSLSSKLHGM ERCMRPLAPA
AFALPAMRHA DHMVELFGPT VDSERVRTKL MRALASVLEP VVSVATFYPS GSYPLKTYLP
DSDIDVCLVL SDDTASATWH ADVTQALLAA ATSDQKVECT VRNVTFVNAE VRVVKCTIDN
VSIDVTANRF GALGAVSLLH EMDLRVGQHH LFKRSLILIK TWCMYDSSRF IASSSSSSST
GRSNILGAVA GALSTFALNT MVLCLFNLFG KRICHPLQAL IEFFHFYADF DWTYHAVSML
GPVPIASLNA GWRPSVRSSD VVMDEVAVDA FKARIETVHG GIRPSLPFQV RACNVVDPLN
ECNNVARSVT ADKLAEMKHA LQHGRQTLVQ IFYDAWHLAS SAKKDDVHAE DIVAALDPRT
LDSFFLNGWT TYGSGYRPDL LVHPRQVWHP PAMNPFGDGN VAIDVLASQV ADLRQLP
//
