ID   A0A067CJ59_SAPPC        Unreviewed;       976 AA.
AC   A0A067CJ59;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=SPRG_07995 {ECO:0000313|EMBL:KDO26591.1};
OS   Saprolegnia parasitica (strain CBS 223.65).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO26591.1, ECO:0000313|Proteomes:UP000030745};
RN   [1] {ECO:0000313|EMBL:KDO26591.1, ECO:0000313|Proteomes:UP000030745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO26591.1,
RC   ECO:0000313|Proteomes:UP000030745};
RX   PubMed=23785293;
RA   Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA   van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA   Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA   Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA   Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA   Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA   Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA   Russ C., Tyler B.M., van West P.;
RT   "Distinctive expansion of potential virulence genes in the genome of the
RT   oomycete fish pathogen Saprolegnia parasitica.";
RL   PLoS Genet. 9:E1003272-E1003272(2013).
CC   -!- SIMILARITY: Belongs to the XPO2/CSE1 family.
CC       {ECO:0000256|ARBA:ARBA00008669}.
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DR   EMBL; KK583223; KDO26591.1; -; Genomic_DNA.
DR   RefSeq; XP_012202733.1; XM_012347343.1.
DR   AlphaFoldDB; A0A067CJ59; -.
DR   STRING; 695850.A0A067CJ59; -.
DR   EnsemblProtists; KDO26591; KDO26591; SPRG_07995.
DR   GeneID; 24130241; -.
DR   KEGG; spar:SPRG_07995; -.
DR   VEuPathDB; FungiDB:SPRG_07995; -.
DR   OMA; AENEFLM; -.
DR   OrthoDB; 178772at2759; -.
DR   Proteomes; UP000030745; Unassembled WGS sequence.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR005043; XPO2_C.
DR   InterPro; IPR013713; XPO2_central.
DR   PANTHER; PTHR10997:SF8; EXPORTIN-2; 1.
DR   PANTHER; PTHR10997; IMPORTIN-7, 8, 11; 1.
DR   Pfam; PF03378; CAS_CSE1; 1.
DR   Pfam; PF08506; Cse1; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030745}.
FT   DOMAIN          32..103
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   976 AA;  108730 MW;  5BAA73F36A47A725 CRC64;
     MAMNMGSPAE LTALVGVLEQ SLSPLAEPRR AAEASLQAML KQPNGPLLLL SVLRASEVPQ
     AIRLSAAIAF KNTIKKDWDP EDGSIHVECK ALVKEHIVGL MCEMPESLMK QLSAALYTIG
     EYDFPNQWPQ LLPQIVEKLG NPGSDFRAIN GVLETSNAIF KRFRHAFKSD ALFLELKYCL
     EQFQAPLLML FGSLTARLQQ TSDLNDVRAI LTALRTMSRI FFSLNWQDLP EYFEDNIKSW
     MEAFEFLLKY ENAKIADASE EVEVDLITLL HSAVLDNITI YAEKYDEEFG PYLPSFTQTI
     WHYLSTKLSL FPKHDDVAAK SMKFLRSVAL QGINNHLFES ESVLSELCNS IVVRNLQLRE
     SDVELFEDNP LEYIRKDIEG SDGDTRRSAA TELLRGLRSK FEAAVTRICL QTITVLLQEY
     TASPQTKWMQ KDVAINLVTA LAAVKQTRTR GVSEVHPSVP LLDIFQGHVL PTLQSPDVTS
     PTSLLLIAGA LKFVATFRNQ LPAHLTQQLF PLLSSCLLPD QFVVHSYAAY CIEKMLTVKD
     GNERRFTKAM LQPFLAPLLN QVFTILVAPS YPENDYLMRM VLRLFVVAQE AVVPYADVCV
     QQLTLLLSQV CANPSNPAFS HCLFEALSML INNVCKANPA FVETFEQLLF PPFQQVLMSD
     VEALCPYVYQ VLAQLLDLTT APTLSSAYHN LFPVLLSPAL WERVSTVAAI VKLLEAYLRK
     YPTAVASHIQ GILGVFQKLV SNRTTETQAF ALLKPILVCL PLASYEPLLV EIVKILMMRL
     QTRLHGRNGT LYVKEMLLTL SIFMAKHGTT RLVNAVEGCQ TGMMGMLLPI WIEHIVRVSG
     ADKKPAVVGL TLLICDSPFK QDGNAIRTLL PALAALLLEK ENKSAHIAVK TEDDILLDLE
     ETGYDAGFSS LHFSSAAGAI DYLDFIPNHK RMLCESMSQL SRATPGGLVN LANEALSPEL
     LQAWTATFAA ENIPLM
//