ID A0A067CKU6_SAPPC Unreviewed; 1586 AA.
AC A0A067CKU6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPRG_22140 {ECO:0000313|EMBL:KDO29815.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO29815.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO29815.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO29815.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KK583204; KDO29815.1; -; Genomic_DNA.
DR RefSeq; XP_012199568.1; XM_012344178.1.
DR STRING; 695850.A0A067CKU6; -.
DR EnsemblProtists; KDO29815; KDO29815; SPRG_22140.
DR GeneID; 24142523; -.
DR KEGG; spar:SPRG_22140; -.
DR VEuPathDB; FungiDB:SPRG_22140; -.
DR OMA; PRICEVA; -.
DR OrthoDB; 55984at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR17616:SF8; YES-ASSOCIATED PROTEIN HOMOLOG 1; 1.
DR PANTHER; PTHR17616; YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 8..41
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 42..75
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 145..202
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
SQ SEQUENCE 1586 AA; 169498 MW; E31CB7530D7A3900 CRC64;
MATDGSWRAM DVGWEQLEDA QGRVFYVNHA TRETSWTPPS TLPLPAGWEE MRDDQGRVYF
VDHATRTTTW IDPRESQINQ MASELDRYAT ERESSVISAT TVSVAEPEPA VLVAPVVVVQ
KGLSASWAPI PDVKATYFAP YIVPDAARMD CTQCRLKFGV LRRRHHCRLC GGLFCGDCTD
KVAIPSLDGR QSACKRCQRN MAAGDTTSIV GLLGLLTQGA STPVPQTIER LRALAKLLLT
PRQETDPLLK NVDPQDVQIY ALLVLSHLTA LYNRMALPVA GEMAAASGVC NTIALCLSMA
VPELEVHALH AMYHLCASGS AACLKALRTA GAGAHVLEIL IVSESVDVKR DAVQCLGAYA
KDVENVKDCI AHNGAHVLTS ALLVLAAAGD VVGLRAVLST LPQLLSAMTP DQQREFALDP
TLVAQCYAAL TPLLALDDDE LSTGTFALLY ALATDPTNAA LLAQNSALLG VLTARLDDEH
DQADAIRVLA AMVRPLERGI VLLPALAAAN TLVAVMTWLH TSTQSVPFTA TIQAQAEMFV
LISAFATVPE YANVVVHCHG VASTLAVLFH AHELLDASLE LLSRLSTAVG GVVAEVVEFG
ALEAIESAFQ DPTASKTTKE ASIAFLEQLG RQMAPTTTVT FATADVLFSL VADDRFERGA
LKAVTTLCAT RPALQARAIG SLYPSTLHAF VLHGYIARDF LLEVLTCLAT LTSLPALLDA
GGLTAACAVL QRQEATLSDP AIAAQALDLL LSMLKTGART SGWSHPPTMQ TVWSALMTFL
VNHATAAELV PKALESVHVL LLHSVWKAQF VTLYISGSSA HAACLDFMEL LGELLEKAYT
GTSPSLLARL LSIVSELAAT HSALPYLLQA DSPDSSRAAL CDLASKDHVA STLTLLEFAL
SEGCDMGLVW ATINTYRARH LLVSAIADIF HDDDVGTREA CVVLTAFVSR PPLKTAEVNV
LCEVAPRICE VAGAMRSVAL PLLVALVAIP RVALALIDGG AIEYMVAFLQ TSAGTDSDLC
QRVLVHLSQI TLGTERLSLC NGVSTLLSFV QSLASTDAHA PNVLAILQVL HLVASKDKAA
RLVLAEAVDL YALLLQHSMQ PDASDAYSCL DSVARPASTS KYTANAPLAH LVVDLLVRVC
AVADARSHIV GRSDIYAELY MWLQYITERS AVEHNSIAIG SLTLLRYRYM ARLAPAEMHD
ALWDLLAALA APAFLAVHEE VARTIAVLCT CVSDPSRCKD VLYRVEVHVY EALSETCALR
HAWLDVALSL GHNRVRDVFP MPLLQWLVVA SLDDMVVRPL AVHVLDVLCY DAAFHVAILN
NQNVLQWLAA HAATDTTARR ISRVVSEDAI DEGAADGAFG YGPVRTDAVL ATQLSRDLES
RYSGYSDNFS SSYGDNYGSA SSFAPGSYSS YGEYAPSSGS TNYYNEAVID DEDVVCPHCL
GNVHVPPGCS AYLHTIPCPL CQRPLGGSSP APAPPGTTTI TCKGCRRGLH LPEGLDLADV
VCPECNSVNK IEPTPKPTLV KCGHCHKMLS APPGQPTIQC GHCKGVSRVM GSDDVVKVTC
AKCKTLLAVP SGSTVYKCLK CGHVSK
//
