ID A0A067CN49_SAPPC Unreviewed; 446 AA.
AC A0A067CN49;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Isochorismatase-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPRG_07253 {ECO:0000313|EMBL:KDO27976.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO27976.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO27976.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO27976.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; KK583214; KDO27976.1; -; Genomic_DNA.
DR RefSeq; XP_012201425.1; XM_012346035.1.
DR AlphaFoldDB; A0A067CN49; -.
DR EnsemblProtists; KDO27976; KDO27976; SPRG_07253.
DR GeneID; 24129539; -.
DR KEGG; spar:SPRG_07253; -.
DR VEuPathDB; FungiDB:SPRG_07253; -.
DR OMA; CPMTTAL; -.
DR OrthoDB; 72089at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00431; cysteine_hydrolases; 1.
DR CDD; cd04818; PA_subtilisin_1; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR PANTHER; PTHR43540:SF1; ISOCHORISMATASE HYDROLASE; 1.
DR PANTHER; PTHR43540; PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR Pfam; PF02225; PA; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
DR SUPFAM; SSF52025; PA domain; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745}.
FT DOMAIN 47..122
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 256..436
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
FT COILED 156..183
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 446 AA; 48338 MW; C1F64FD758B1176E CRC64;
MSMLCSFVDV QGDLYYCPLA EFSSAYATPR LEGALVVADP ISGETPLRNA KAVAGKIVLM
QRGTCDFVTK TIHAQKAGAI GLIVANTDEE NPQLAFVMDA GLQRAALRSR IPAVMAPFET
AQYLLDLLGD SDAMCMHIAI VLLNAAEAST VLDAQASEKR RQLAEAEALL KQQDRERQQR
EATLLLRSRL AKEASMTKFV SPEPSTTPAL FCEAVPLPSA VAVAVGTPHL DTKCISPRAA
PRFDTKPDGM TSLATGLLVL DMQYYCAMPH VGKFANQESL NAYYFDRLRK VVVPNVQRLL
EAFRARNYDI IYGTIESATK TGRDRSKAHK IAGIHVPRGS FEAKVLDDVS PLEADVVVPR
TAHFGTTNVD YLLRNLGVQC VVVTGVSTLG SLEAAVRGAM DRGYATIVLE DAIAFETSDE
HDAVMRAMDR IGAGYMASTS EFVQSL
//
