ID A0A067CNX5_SAPPC Unreviewed; 2771 AA.
AC A0A067CNX5;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=BEACH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPRG_06255 {ECO:0000313|EMBL:KDO28206.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO28206.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO28206.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO28206.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
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DR EMBL; KK583212; KDO28206.1; -; Genomic_DNA.
DR RefSeq; XP_012201031.1; XM_012345641.1.
DR EnsemblProtists; KDO28206; KDO28206; SPRG_06255.
DR GeneID; 24128611; -.
DR KEGG; spar:SPRG_06255; -.
DR VEuPathDB; FungiDB:SPRG_06255; -.
DR OMA; CITHTHR; -.
DR OrthoDB; 49444at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006816; ELMO_dom.
DR InterPro; IPR046851; NBCH_WD40.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743:SF112; BEACH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF15787; DUF4704; 1.
DR Pfam; PF04727; ELMO_CED12; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF20426; NBCH_WD40; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51335; ELMO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1741..2009
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT DOMAIN 2493..2657
FT /note="ELMO"
FT /evidence="ECO:0000259|PROSITE:PS51335"
FT REGION 1133..1156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1197..1222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1534..1612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1555..1569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1579..1593
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2771 AA; 306843 MW; 7C443AF887A9AD7D CRC64;
MNASTIDSLV RTIRFPDQLA RVFTDFVGVV DEPQQIELLD ALTFMVKHEA ANAQACIQVA
FHRQIVASLE AHALLLGFSR PILKKILALL MQIAQYSVTA DDIRAMLQVF QSPRWKDVAP
DDNAVATFIA SMEMMARSAP GPSWYLDLSG DQSGFVVPSM ETVTFPPSGY TLSTWIRVES
SPGMNSPLFS FCTEGNVGVE VSFMDTTLVV KSLDVKKNEY NEAQVPNALV KHQWQWICIV
HTYRQFRGSK LDVYVNGDAR QSFRFGYPAI ATTPGTKMKC YVGRTKNNYS RCLIAHVGSI
AFFSQPLAAS VLEGIKSADD YDNVVLQFNA AVMSSSLTAS APLSGAAAAP SAPTSAGAPH
EGLVFAFDAR SYDEKHKLLL DASGNMHHGE NIGSAPSVRL RTISTFKDSV WQMGGPMIFL
PLFVSPLAEA GPLDLNACQT ITRPLGPLSI PKMISLLAET LRHSTINKFV CRRSQTIPLL
ALLLRSLPTT YLTPDLLSTV ERLLSAVASD RYLSDDIQKN LLYNFQLWVP AAVEIQNTIF
EKLHIAVISI RYMLRMLSSV YCKSNLTTKS PADAAHLRNR VLETIRMLLY DPEAWKQGQK
KSLVSGLGLI GAAPPSSMML SFDAARTLIF SMLGKPTNPD GIVDDAIKVA VSEVEIDAGS
IAEHVSDSDI PDLLQIVIDL SITAETQTEF LSVFERLGGL RIWLPLIATD NAPVRRMTLR
LLRTYINFKC NLNATPTLKP SLSAIDVRMI LEALNVQEYP LHLGSFNELY SLLLGIDYGD
PAVHLFQSDS DDVHDHAALL SDATTTSNVV RHPSMLLPFL ELLKQSPLHI RWAGFVYWKL
LFGDDSIECT INRRTLLQCY ATHAYPPVAI EAMFESFLSV PLPASATLFA DACPDADHAP
ADTTTLHLRE VVANASLTDT ERLRAATALA RFQDHKYLVD VVAQDGARRD QYRRLVGTKE
TGPLLSDHLR THLMYLLVSV APGVVHSFVG GACLELAAQL VVLEFKTNES AGELVLHPLA
LYPPSSRAVV SWLKAILDRV THLVDIQVPP RASVCWRNIE HVCSVAASVV FHFDPDVPST
KRRDSTMDDT AFWKCREELD GERDLCESLL NIWQRCASQL TFDLDATFGR TAQPRASLTT
TPSQRPSLTM SNSMPKRGSF APLVPSALKP FPGGAMRQIL GLVLRSMYQV LYDDEAKDDC
DDESSSSDDD DASRAPARRR SRLNSMPLPM DAVFVAKLNK LDYFVQVLKL PQFVATKEDT
SLVHWFVLEL ARLMHHTQSL CASEPRWMES ARPHYALPAS DARVTDELRH MLQREDFVLT
ETEVYRRDMF YHEHLETLRD SRLKKRAAFQ SAVENETDQA RSAIQIVFSA GVQARPSSDP
VWRKRVLAKE YDDWMKLERL LRWNIQHVWS AQFETTASNW QLDAFTSSKW QRCRLLPDVA
RSEPYTKQQS RANASTTDAF LAQESGAESG ATSPYLDDLE IEEEYNNDTE DDESHTVNHL
LGHQDDDSAI EVQIAAAIDE ATAALERARS ASILGVDGPP LPTPAVPVDD APTAPAETSS
ETKRASMSSR FMTGFGRFRK PSSMSSDHND PTEATTTPPP PPTSATSLSP KAADKKKVAV
NASFRTTAYL LLPEGRVVYG MFRLGQASIV FEGEKVVDED NIDAKTGLVL LKRRIFSVRV
VKAVYRRRFR LDMGCGMEIY FVDGTSLLLG FDSDQDVDIV YSVLRQRKPP CLVTTKRLLT
GDRLVAHSTW HATTQWVRRE ISNFEYIMLL NVAAGRSYND IAQYPVFPWV LADYASETLD
FEDPSIFRDF AKPIGGQTTE ALESAGARFA SSGAFPYHFG SPYSSQDGVL GALVRMQPFT
LAFDALRKPA SYALTSIPAL YAQCTSSTNE RGWELTPEFY MSPHFLMGSV RFEAVVLPPW
AHGSVDAFIR TQVEALESDY VSCHLHLWID LIFGVNQRGP DAVAHGNVFH PECYPDNLKL
KLLDKCARDR IAQRGTVPSQ LFHKAHPTRL SVDDALEKRY PASHALASLS SRSQVRRYDV
PSRHEMALSS VRFSTATATG HGMGVVKNVA AKVKASDDAP AGSVVYTTDE SGLVLAKRYQ
NATPDSAKGA PFTLQEVEQW WRLPAMCSID DGLVFYEHMV SCGYFDGSWR IHWSADGELL
QRIAFHKQRI LCMARSEDDV TGDVALAFGS EDCTISVWAI SKYAASRPRR MFSSGSKKEL
PVGALPWVLL VGHTRPVVSV ALNVHLDIVA STCRGHRLLL HSLRTSCPLH TMDLSLPSVV
DTSIYLTISC EGTILSHAVH TLDASASDWR NTATQSELAL VSINGRVVSR VQMKDKDEPL
ALLQRGVVFT SDGQFVITAS AGRDGGLDVR PIGDLTSVIR RIETKRSCAL TCFGLSQDER
CVVAGYEDGS LVMYALHYGI RDAGRVLSDK KARAEEAAAF ARATASVVND IKEATTVFLP
KGKYSSALDP VVLANMNKLF LLSKRPCVGG NSDYEELLCT FWGIIYSSTD ALFDPAFERS
GDSWSRLGFQ RPDPTTDFRS GGLLSLNCFI YFATTSIDEV KRMTSSQIPG SHEHTYPWGP
VGINITCLLA RLLWQNDGEL FLERENIWPI FANADAFYTL FAEVFLLFDC IWCGMNAQYS
SFSVVMEFTM QQVNEVLKEN HGSLSNLQWN IQMRRGQFQQ SFTPDPIVAQ VTETAPTSSM
SSSAIPDSFN LLDLASPPRI AATTDPFDVF DPFAANTLIN VSSTHSVDMS TMPTNFNSNG
SGHYDPFAGL D
//
