ID A0A067CP64_SAPPC Unreviewed; 697 AA.
AC A0A067CP64;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=SPRG_06366 {ECO:0000313|EMBL:KDO28316.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO28316.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO28316.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO28316.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SIMILARITY: Belongs to the calcium channel alpha-1 subunit (TC
CC 1.A.1.11) family. Two pore calcium channel subfamily.
CC {ECO:0000256|ARBA:ARBA00009286}.
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DR EMBL; KK583212; KDO28316.1; -; Genomic_DNA.
DR RefSeq; XP_012201135.1; XM_012345745.1.
DR AlphaFoldDB; A0A067CP64; -.
DR STRING; 695850.A0A067CP64; -.
DR EnsemblProtists; KDO28316; KDO28316; SPRG_06366.
DR GeneID; 24128715; -.
DR KEGG; spar:SPRG_06366; -.
DR VEuPathDB; FungiDB:SPRG_06366; -.
DR OMA; NMESTEH; -.
DR OrthoDB; 5403296at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR044581; TPC1_plant.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR46988:SF4; ION TRANSPORT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46988; TWO PORE CALCIUM CHANNEL PROTEIN 1; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 50..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 633..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 343..378
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 697 AA; 78614 MW; 4A45CCDDF6C7AE86 CRC64;
MDETAPLLPR RVESDEDVLF SAAWLVEDAL LGYTRPRPLQ THLAYQLYEW HAHCAILSDV
AIYVLIALAF VEVPHWCNHD PATLFACGDP SSPETPMTFN AGFLTLAQSR SVALACLLFL
LADVLFGYTY LGAAFLGRHE RKVQLGLVVV SLVDVMGALA WPAYADTVAS LRLHEYARIV
MFVFSQHELR RALRKILRVV AEVRNILSLV VVFILSLRTP EGVAQMPNIY EACWHFMILL
TTANFPDIMM PAYNSNRSVV LFFIFFLCFG LFFLLNVVLA VVFNNFARFS DAELALSDRI
RTEKLAHAFE CLQSLSNHPE TVPMDVCLRL FQGLHRFRNI SHLERDEMTA LFDALDANGD
HVLDLAEFLH VCEAVERVLI KEPQPASEVE VYCPRLFTSV AFQKLRAAVR HPTLEVTIDV
VLVANAIVVF VESFSILNDA EAKVLLDTSA WTIWDALELG FTLIYLVEML AKMLVYGLRG
YWISIKNRFD CVITLAVVAA DAYAYLPGTS LQVVKILLIA RCLRLFRLII NIKGYRVICT
TWLRLLHFGQ HLLLLTFCAM YVYALLGNQL FGGRISPGRM RREFPESAYT QADYMANNFN
DMPSAIVLLF ELLLVNNWFV LADGHAAVSS KYARWYFIAY YVTGVTLLLN LVVASILDSF
MDEYKHEHGQ DAAVAGACLI QPSPPPPATK TAVDRRI
//
