ID   A0A067CTE3_SAPPC        Unreviewed;       566 AA.
AC   A0A067CTE3;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Hsp70-like protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SPRG_01255 {ECO:0000313|EMBL:KDO33979.1};
OS   Saprolegnia parasitica (strain CBS 223.65).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO33979.1, ECO:0000313|Proteomes:UP000030745};
RN   [1] {ECO:0000313|EMBL:KDO33979.1, ECO:0000313|Proteomes:UP000030745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO33979.1,
RC   ECO:0000313|Proteomes:UP000030745};
RX   PubMed=23785293;
RA   Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA   van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA   Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA   Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA   Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA   Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA   Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA   Russ C., Tyler B.M., van West P.;
RT   "Distinctive expansion of potential virulence genes in the genome of the
RT   oomycete fish pathogen Saprolegnia parasitica.";
RL   PLoS Genet. 9:E1003272-E1003272(2013).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|RuleBase:RU003322}.
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DR   EMBL; KK583191; KDO33979.1; -; Genomic_DNA.
DR   RefSeq; XP_012194867.1; XM_012339477.1.
DR   AlphaFoldDB; A0A067CTE3; -.
DR   STRING; 695850.A0A067CTE3; -.
DR   EnsemblProtists; KDO33979; KDO33979; SPRG_01255.
DR   GeneID; 24123853; -.
DR   KEGG; spar:SPRG_01255; -.
DR   VEuPathDB; FungiDB:SPRG_01255; -.
DR   OMA; LCMSVNA; -.
DR   OrthoDB; 65449at2759; -.
DR   Proteomes; UP000030745; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd10170; HSP70_NBD; 1.
DR   Gene3D; 3.30.30.30; -; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375:SF144; ENDOPLASMIC RETICULUM CHAPERONE BIP; 1.
DR   PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU003322};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        533..554
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   566 AA;  60581 MW;  21ADF189E23E34D8 CRC64;
     MSSSDATYES WGANAHEFRN GTVCIGIDLG TTNSCVGYWK LHANHVKIVN HSAGDTKAKT
     LPSVVSFPPT GAPAVGFAAV AAEASDADVV TVRSAKRLLG QSLADASPDQ KYLSYTLCDG
     ESGHVSIALP ARKTSVTPSE VAALLLSKLK AAAEAKLNER IANCVLTVPA YFTEPQRQAT
     LEAAAMAGFS AVRLLNEPTA AAMAYGLFVA GTKRVVVFDF GGGTLDVSVL HIADGTFTVE
     GVGGDTHLGG EDINNILFDH VLQAIAKKHG PVSLPLATHD MVQLQRAVEA AKVALSTDDE
     TVLRLTNVGH VALHEMTLTR RKLDALCDPL YKKCLRITRE VLKSIDVDPS DVDEVVLVGG
     STRIPAIRAR LRAFFNDKEL CTSVNADEVV AEGAAIQAAI LSGVDKKVFQ DVLMLDVIPM
     SIGIEKADGA MEVLIQKNSR IPVSVTKYFD TAIDDQAGFT IEVFEGESPV ARENTYLTYF
     DFVLPRKVRG KAGAIQHPVT LSMNANGLLQ VKAGILHDDA IDAEDASEAQ RSMLVLCVYM
     GCLIAVYVFV RLYFADQRLY ASVDEL
//