ID A0A067CUP6_SAPPC Unreviewed; 1352 AA.
AC A0A067CUP6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=SPRG_19786 {ECO:0000313|EMBL:KDO30231.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO30231.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO30231.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO30231.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
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DR EMBL; KK583202; KDO30231.1; -; Genomic_DNA.
DR RefSeq; XP_012199039.1; XM_012343649.1.
DR STRING; 695850.A0A067CUP6; -.
DR EnsemblProtists; KDO30231; KDO30231; SPRG_19786.
DR GeneID; 24141067; -.
DR KEGG; spar:SPRG_19786; -.
DR VEuPathDB; FungiDB:SPRG_19786; -.
DR OMA; KITHATQ; -.
DR OrthoDB; 70365at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR006585; FTP1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR PANTHER; PTHR22870:SF437; X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR-RELATED; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF00415; RCC1; 3.
DR Pfam; PF13540; RCC1_2; 2.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00054; EFh; 3.
DR SMART; SM00607; FTP; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 3.
DR PROSITE; PS00626; RCC1_2; 2.
DR PROSITE; PS50012; RCC1_3; 4.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 50..85
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 86..121
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 132..167
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 695..746
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 747..828
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 829..894
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 904..949
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
SQ SEQUENCE 1352 AA; 148942 MW; F7E70118CEE62A46 CRC64;
MAPEPVAKKS LFRNKAAAPP SNVIVVDGIP LSRDLVEDPS LSDAPPEAEN AFIDAEAMFR
KYDIDRSGGI DLDEFKLLLV DLQIDIPPPK IQVYFRKCDL AQKGFITFDE FRLAMFTCDP
TNPTRTNGFC PSKVLNPKDL FAIFDTDDSG EIGRSEFSAI LRFLKIKMAL DRQETVFSQF
ENPVTEGLTY LAFRSLWLTL VDVRKELHNR NIAYNKLLSR AKLAKKLESV LDKEDAQEQY
TMLEAQWNFN WETIKERREK LLANAKRYAD YVLGETLDAA GQVYVFGKGS FNRFDGAPAE
RDFVECPYFS QLLALWTSRV RGAEAFAPKA PTSPEKKLGG WDSPKKRPPM IKTERIARDP
TQTQQLAFHN RVVAINTAWL WARRVKQVSC GASVAYALTD AGELYCWGGT RRTWDYVYSP
EHSADPSHQV PGAAASRPFT ARTEMLKLSA PNQLLADEHE HLKNYVRSMF RENAPPEVPV
ESDEAELQRL LVLIDYFELY PPALRAEVNL AKARELMEFD LRADVVTNAL RLRALQSSQT
GKATNATKLS KCLMLELECM GEPFQRQMKK LDQQLLRALH NYQDATISSV LKKGAALWQH
MRQLVTAIDE TETSAFQAKQ DLWEQKRSEV GRLRRKQARS GLEGATLGAV PDHEKTLQMS
GVTARGPRQK TFLGHQALQQ VSVGAKHALA VHQSGQLYGW GFGTYGRLGS SSHDDTTTPK
PLAHLREMRF RSVACGYSHS LALRHDGQVF VWGSGATGKL GLAPPSKEPA IARPHTTPVG
HRHANTTEPV RVSSLEDCFT ILPLPLALPS KVRKIACGPS HSAVISTNGE LYVWGSGDGG
RLGLGDGRFT DTDNELRGGH LGIVSVPTKV AALLEHHIID VSCGTAHTAV VSAIQSNGAL
SSGGRVFVAG SAHALGDFCP AFVTPTGLAS VQVTALACGN AHTAAVSIDG ELFTWGNNVG
GCTGHDSSHR FIGTPSRVPC IYQSPSNMAR HPSYAIVALQ SSVATGYGAH LALDGVTDGA
LESNCCQTFR EMCPFWQVDL GVMCRITSVR LWNRPGATGD QLFPCIVCIG QEPFEAEAGK
HALHEAKAHS VFTKFKLETA ANPLVWHPPD NTIGRYVRVQ IDGASILSLA QVEVFGTEEW
VYQGPRVHSV ASGDDILVVI CRPTYAQSDI DKAYLRALSA DSRFQSVLDE FPTFDTSKMA
LDDLRRAARD CPLCTVQRVC PLCLLCKELE SHEHDLAADY RATMSLDEIG TFLLSLRPPK
PLAPLAVDEE NRLARIYVDD EKPESALHKA EGRVLAAMSK VVRGGPKSPS FLRKAMVSMA
TSRLAFAKRK VPEMHVQIVR PHTTSVLGRG GL
//
