ID A0A067CX39_SAPPC Unreviewed; 506 AA.
AC A0A067CX39;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Ammonium transporter {ECO:0000256|RuleBase:RU362002};
GN ORFNames=SPRG_04235 {ECO:0000313|EMBL:KDO31096.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO31096.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO31096.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO31096.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362002};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362002}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC family. {ECO:0000256|ARBA:ARBA00005887, ECO:0000256|RuleBase:RU362002}.
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DR EMBL; KK583199; KDO31096.1; -; Genomic_DNA.
DR RefSeq; XP_012198225.1; XM_012342835.1.
DR AlphaFoldDB; A0A067CX39; -.
DR STRING; 695850.A0A067CX39; -.
DR EnsemblProtists; KDO31096; KDO31096; SPRG_04235.
DR GeneID; 24126695; -.
DR KEGG; spar:SPRG_04235; -.
DR VEuPathDB; FungiDB:SPRG_04235; -.
DR OMA; GFPTTPM; -.
DR OrthoDB; 1109542at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR001905; Ammonium_transpt.
DR InterPro; IPR018047; Ammonium_transpt_CS.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR NCBIfam; TIGR00836; amt; 1.
DR PANTHER; PTHR43029; AMMONIUM TRANSPORTER MEP2; 1.
DR PANTHER; PTHR43029:SF10; AMMONIUM TRANSPORTER MEP2; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
DR PROSITE; PS01219; AMMONIUM_TRANSP; 1.
PE 3: Inferred from homology;
KW Ammonia transport {ECO:0000256|ARBA:ARBA00023177,
KW ECO:0000256|RuleBase:RU362002};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362002};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362002};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362002};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362002}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..506
FT /note="Ammonium transporter"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001635046"
FT TRANSMEM 65..88
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 150..173
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 220..246
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 258..277
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 289..310
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 317..335
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 341..361
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 373..394
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 414..439
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT DOMAIN 65..466
FT /note="Ammonium transporter AmtB-like"
FT /evidence="ECO:0000259|Pfam:PF00909"
FT REGION 472..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 53733 MW; 1742C8FA9A9DCE9F CRC64;
MQSNSATWHL AAFLALAAVT SAASNVTCAP SQYLDAATNG CVDYVNQGAK AAAVVDGTLD
SGNTAWMLMS SALVMIMTPG VAFFYAGLAG EEMASNTMMM SFVSMAVVSL QFWLFGYSAA
FSSDGVFTWT FYNHVGKLPS GTYGNGTPHV LFAFFQTQFA MVTPALLSGG IVGRMKFGSY
LLFIFLWSTL VYDPLAHWMW SQHLDASWVL EPFGWEGKMG AIDFAGGTVI HISSGFGALA
GALIVGRRYN HNETVKPHNV PLVMIGTTLL WFGWFGFNAG SQGAADGIAA IAAINTHLAP
CAGFLTWTFL EFALYKKFDP CGAASGAVAG LVAITPACGY VLPWAAVVFG IVGAVTGFGA
VRLKNSMRYD DTLDSFAIHG CVGVMGGLLT GLFANPEVNP AVVGGAFYGH GQQFVHQLVA
QCVAAGYSFV VTLLILVALK YTIGLRVSEE SEMNGMDVTY HGGLAYDYAP KTRHSNESSG
PTTGEFQVMM TPSTTDPDKE KSHLHV
//
