ID A0A067CXH8_SAPPC Unreviewed; 494 AA.
AC A0A067CXH8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPRG_01256 {ECO:0000313|EMBL:KDO33980.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO33980.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO33980.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO33980.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
CC {ECO:0000256|ARBA:ARBA00024041}.
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DR EMBL; KK583191; KDO33980.1; -; Genomic_DNA.
DR RefSeq; XP_012194868.1; XM_012339478.1.
DR AlphaFoldDB; A0A067CXH8; -.
DR STRING; 695850.A0A067CXH8; -.
DR EnsemblProtists; KDO33980; KDO33980; SPRG_01256.
DR GeneID; 24123854; -.
DR KEGG; spar:SPRG_01256; -.
DR VEuPathDB; FungiDB:SPRG_01256; -.
DR OMA; WIISPAK; -.
DR OrthoDB; 36008at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015203; F:polyamine transmembrane transporter activity; IEA:UniProt.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR044566; RMV1-like.
DR PANTHER; PTHR45826:SF2; ACID PERMEASE FAMILY PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR PANTHER; PTHR45826; POLYAMINE TRANSPORTER PUT1; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 494 AA; 53461 MW; FA8C7E5AF47D66AA CRC64;
MSVPSPVAYT AAATGPHQVQ VQPSVDEVNP ECQRASLPRL VNRRVLTTLS VAALCYFNVS
GGPVGSSQIF SAGGPLLGLI ALAIFPFIYC IPLALVTAEL STTYPENGGF TVWVFQAFGP
FWGFQEGLWA WVSGAIDNAI YPALTVQLIS TYSESLTEGV SGWFLKVGVA LIYALPNIFG
VRLVGWGMVT LAFIVLVPFI IFTIWAYAAA EDWSSLHMIR RNDTTDTDVG TGPAMIQWDL
LINTLFWNYN GFANASVFGG EVANPSRTYP RALMICTIAV MLTYFFPLSA SSVYNSPTWQ
TWDDEAFSSI AQNLGGDTLL GLITVATVAS NWGQYSSQMF VVSYQLTGMA ECGLAPKIFL
KRAERTDVPY VSVALSFLVI VILVGYEFEV VVNMTNAVSS MSIILLLVAA IKLRVTHPNI
HRPYKVPVST KVLALLLTVP VAMLCYIVYT VFALDTIVPG ILVGVVIIVG ALYAVALKLT
PKHFVDPKAT ASLA
//
