ID A0A067CYX7_SAPPC Unreviewed; 2531 AA.
AC A0A067CYX7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=UBA domain-containing protein {ECO:0000259|PROSITE:PS50030};
GN ORFNames=SPRG_03609 {ECO:0000313|EMBL:KDO31691.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO31691.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO31691.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO31691.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK583197; KDO31691.1; -; Genomic_DNA.
DR RefSeq; XP_012197577.1; XM_012342187.1.
DR STRING; 695850.A0A067CYX7; -.
DR EnsemblProtists; KDO31691; KDO31691; SPRG_03609.
DR GeneID; 24126101; -.
DR KEGG; spar:SPRG_03609; -.
DR VEuPathDB; FungiDB:SPRG_03609; -.
DR OMA; GILIRMT; -.
DR OrthoDB; 1695at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd14327; UBA_atUPL1_2_like; 1.
DR Gene3D; 6.10.250.1630; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR010309; E3_Ub_ligase_DUF908.
DR InterPro; IPR010314; E3_Ub_ligase_DUF913.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR11254; HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; 1.
DR PANTHER; PTHR11254:SF446; HECT-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF06012; DUF908; 1.
DR Pfam; PF06025; DUF913; 1.
DR Pfam; PF14377; UBM; 3.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1186..1227
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 1780..1869
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1911..1946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2031..2050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2201..2236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2476..2512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1821..1869
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1930..1946
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2480..2497
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2498..2512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2531 AA; 275939 MW; F086592C3A1EEF32 CRC64;
MICGAGAPRY PPTEGEQALV DLLRLRDWPF EAQADLYNYI PLLAAFGKLL DRIVTRAATD
DGRPIVIFHN GDALAPGAWT YAARDELAYE VLRVSAILSE NATNKHLYPS IDHLVLLVGA
TSERIAREAI KLVAMLALPS LPHRYATDPR APNDVKARDR TLLKKYLLVV AEGSGGASSS
LDMVDYLQDD ATRTEATRPE MVYQFYRYDE VAKDSVLVSI KIPDPPAQVT PTTAANVLAQ
LIQEHHVPEK HQFKLLYRIR SSYSAASRST REAAVVERLH ALLGLFYIFG DSEEVTQYME
ANAELVVEIV ELIRYDIHPH VPLPVRVAAI QVLTALVSDG VVQSRGVRDL SRLQSSVLSA
LGVVRGMPHG AFLSLVRHTM GTLSSLTLSQ DKSPDADMDM TLAVAFVQAT TSTADWTPFR
DLTQSTDRQL YWVESVLGLL SVVVGIPSGA SALTESGIIP SLLHAISCPS LSPLHTSVVV
QCVQALECVV TNHAPAASLY RDLSGVGILI DRLAADLHAE SVHGTQQILL LTLLNMLSVS
FHSQGVMSAG ATSRVIRDTA PLAKVLLAIL SNVDAYGSML FAQAATLVSD IINNDPTSVN
HIHASGLAEA FLKTLCRWDL TNGSNALPPS PELVIAVPSV LSALCLTSTH VEKVVAYEPL
TYLLDMFVMP GYVLYHGFDS LQGDVASIVG GGLDELMRHV PAFQKPAITA CVRALTQVQS
YSDATSDDET RHTAVLRMTM HVCDVLETVL AKAEHAARFA DLGGVDTLLT LYSRILPSTS
AFLASVTQSH ESHASLAHYP AAQGLTVAAR AYAGQQPTTM LTKILQQMTM HLDALPATIG
IASVADVPLA NATVDATFLD AHTQVRSAGN YLRTISVLEW LVSLLLWSLR TAHAHSQSRR
WFAEFTLEKH QNVLAKLFAV DRSVLCERTS LERQLVAKAP VGLWKIGALL LLKFSLMVRN
LVTKYGRTFL AVPAHHRLSE EAVSPLAAHA LPLSHSLHAL LQNLFDSVRG LTLPFEVSFA
GVYYLETLSA LLYEGKRRTA NTVLLQEVVE SGLMASTLQW ISQHALALLD NVAALSKQDL
RFFQTAFQLL KRASDLGAIS NAPLTASLAL LQDANSARPF EPNALKMQLH TLVLKTIVPL
WAKEAQLATL PWDASLSYLF PAVATLLKHR LDVAEKPRAP KPDAFVADEL VIESLTSMGF
GRPAVETALR RVQLNDVELA MEYLLSHPFD ENEVGDVNVA VDETPAVVDA AAELSELYTS
VRSGLERMCF DVVKSQPSDQ RMVVVKVMAD LLLVQCQRSN DERRNVLSQI HAFVLEHAMD
AMTPSTHLLA LLLHADPPSR QVLASLTPSV VTHLLHALQT ATPTSPDDGL TTVLLVLDAL
GQEEGVLTLA MRESLLDTCV ALMQQGVSAN VGHAMWQLLV RLTRDVSIAD RFVTRHGVEA
CLALESRFDG YKELTSALLA HVMEYPQVLQ ARMEEKVLQS LKKLSARFGA PELMRISPRS
LLSELGIVAL RNEALFLDAL KATILVKKSE SGRLYVLPAG NATLVGTQKL LTLPIPNASF
VIKLVVDHLV ALWTAQKQHE SALPMFYLVH LVSLFPTCAN VLLQDHLAFV QLVLAEMLPC
RDLTQLMRKP AATPEETALD RHRLKELTKD RVHNAHRLLL GICATNSESA KRVLAEVVKL
IEAWALAAHG NGTVALSSIH AWCALMLSIL WPRDDVKEKS GLWEHAKWLL KTKTNIVTVL
FDALGKIDLT HPLARTTCNM VLRLLAAFTR PWVAHRLRKV PRKKSTEVED TQAMQVVDEA
PADESMTVDE VSGSAEADDV PMGDGESDDE HGMSGEDMDD EEDDEEEEEE EEEEEEEGDD
DEDDDDEDEL NREDMEMMEA DYPARSRQDD VMHPTQLWDS LDADLSVLHD DDEVAPRAAP
AEDSPQAILQ RARTMASNAT RRSNETSFAN EAQSIFDLFS ASLGSNHRSR NAAWSQLFRE
FEHDLTHRGG ETPDDDSGFV LREFDDDADD PDVMTVPFDV LDRDSRRFRL MGRSTPGVPG
ASRGSRSAAP TISTSSLAGL THPFLASPAV GGELAAELYE FGGMGRGAGD RPPSRHPPSS
RADFHLLSEL SMTPQLQRSN ASRFPRSSNH WEFGANPFGS RDDAVVRSVV SRMEEELNGL
VVADAVPDAT EELPAPAPEA AVADDAVSET ASVIALTSTL GQSSLQSPPD ASMSVASSPL
APADEDDDEP VDTSTSVADQ MARAIQMSLS QLESTTMPPP APSTSSDQLF SFTLDLPTAP
APVPPTHAEA APPAPLAAES VATDEAEAGL VCPAGMDPEV FNSLPPDMQA EIIASQAPEP
PASTSGQSQL EMDIANSSYD RETLEALPAD IRDEILANER REREAAAPAD VSRAQEMDTA
SFVASLAPEL REEILITSDD AFLQTLPSDV RAEAMVLRER HAFRANFRSE PSAGDAARGM
FQRPTLRRML TTHGTDILES GAARRPRSRH DNAPPSRARQ TRRTSACCSS RRKKATWSTS
VSLTRARSRA F
//
