ID   A0A067D1B9_SAPPC        Unreviewed;       630 AA.
AC   A0A067D1B9;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN   ORFNames=SPRG_00127 {ECO:0000313|EMBL:KDO35280.1};
OS   Saprolegnia parasitica (strain CBS 223.65).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO35280.1, ECO:0000313|Proteomes:UP000030745};
RN   [1] {ECO:0000313|EMBL:KDO35280.1, ECO:0000313|Proteomes:UP000030745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO35280.1,
RC   ECO:0000313|Proteomes:UP000030745};
RX   PubMed=23785293;
RA   Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA   van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA   Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA   Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA   Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA   Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA   Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA   Russ C., Tyler B.M., van West P.;
RT   "Distinctive expansion of potential virulence genes in the genome of the
RT   oomycete fish pathogen Saprolegnia parasitica.";
RL   PLoS Genet. 9:E1003272-E1003272(2013).
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DR   EMBL; KK583189; KDO35280.1; -; Genomic_DNA.
DR   RefSeq; XP_012193630.1; XM_012338240.1.
DR   AlphaFoldDB; A0A067D1B9; -.
DR   STRING; 695850.A0A067D1B9; -.
DR   EnsemblProtists; KDO35280; KDO35280; SPRG_00127.
DR   GeneID; 24122785; -.
DR   KEGG; spar:SPRG_00127; -.
DR   VEuPathDB; FungiDB:SPRG_00127; -.
DR   OMA; DWNLVGQ; -.
DR   OrthoDB; 45399at2759; -.
DR   Proteomes; UP000030745; Unassembled WGS sequence.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR024977; Apc4-like_WD40_dom.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13720:SF53; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52; 1.
DR   PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF00400; WD40; 4.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 9.
DR   SUPFAM; SSF50978; WD40 repeat-like; 2.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          107..148
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          112..162
FT                   /note="Anaphase-promoting complex subunit 4-like WD40"
FT                   /evidence="ECO:0000259|Pfam:PF12894"
FT   REPEAT          334..376
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          419..458
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          588..620
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   630 AA;  68197 MW;  475BB288616496F5 CRC64;
     MDGPPAYQLE LEHVIGYTGR SKDTVLAHPR DPDAYFTCMG AAVVISRVSD THAQEFLRGH
     DEEISSLCVS RSGVLLASGQ LPSTKRNGAG AAIVVWDLYA KSELYQLHGF FCKITKLAFS
     PDDHFLLGAG ADGSVILWDL RTSEVVVTRS YGSPVTILNW GKVEEKTRRP KYTLLFAHSS
     QLLVSELSYD IGSMQYKLES YPCAMPSTGM VREYLAACMT QTNDTLLAGT YAGELVVFNA
     DARVFKCTIP ISSNGVHSIV CCAATGYLYV GAGDGVLKKL VGDHSDWNLV GQVALMGAIA
     GLSVTCDGAT VLAGTSAGKL YRILASAMSV EELACSHLAP VTACVFDGHS SEAFATLSHD
     GTLKVWDLSS YRVKASAAEN VHGRCVCYAV NGAFLVSGWA DGWLRAFETA SGHKLWHIAN
     AHRGEVTCIA ANDKCIVSGS SDGGVNVWSL ATRELILQFH EHKRGVTQVC IDLVKAHHVH
     SCGLDRSLFL YDLKTQRRAV VHQVREGAFH AMSQRLDSET EIITGGADGR LLFWDCDVAD
     AVKVLQDPNR MRVLALQVSP SGRFVATGGD DCHLKIYALE SDALMAIALG HSGAINQLAW
     SPDERQIVSV GVDCCICLWN FFLEDETPRY
//