ID A0A067D8Y0_SAPPC Unreviewed; 1909 AA.
AC A0A067D8Y0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=SPRG_00314 {ECO:0000313|EMBL:KDO35467.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO35467.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO35467.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO35467.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KK583189; KDO35467.1; -; Genomic_DNA.
DR RefSeq; XP_012193804.1; XM_012338414.1.
DR EnsemblProtists; KDO35467; KDO35467; SPRG_00314.
DR GeneID; 24122959; -.
DR KEGG; spar:SPRG_00314; -.
DR VEuPathDB; FungiDB:SPRG_00314; -.
DR OMA; VCPQDDA; -.
DR OrthoDB; 6951at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 426..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..552
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 604..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1063..1084
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1261..1286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1307..1335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1355..1377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1389..1409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1466..1487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 691..924
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1530..1763
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1909 AA; 208707 MW; F2C68EC783C5AE43 CRC64;
MLSAAQSPTP VLSAPAQAPD HIRPLLWKNF LLKKKHPVKW ALEMIVPVAF IILLGGLKHL
MDDVKVPSGW ADETNPPGDD TLGTGYNLYA TSRLMNATYS KYYTTESTMA ALLMNLAVQA
FQNAQSMADF TLAQNLSCSA FVVQGKVSLD PTSPNAVPKE CMGRIVPWKI AVVPDTAFTR
NYFAKTIAAW HPAVPLTNTS SILGRPTIPA FGDSIIFFPD EAKLEAHVMD NLYGTDLDHP
RIHSAIVFNA PPAEAQIGSA VSLDYSIRLN STLGRGGIPG DVPRTNLPAY DPLQKSISVT
NYQNYALTGF MTLQTLVTRF ALCQPTYENG APGNCTNVKT TAVASPALDA RLFSQVQNDF
TLQTIAGFFN KLSPTKINFD QIPEASKQAL LTPLRQAPQP YFGQHVYPFP IQGYTSSPFY
TSVSSFFAII FIISYLFSIS SILVALITEK ENKSRELMKI LGVHDRAIIW SWYITYGAIF
VVAAILQAVA SKANLFSNCN VVLVFIFFLL FGWSVLAFGF MVSSVFSKSR IGTYVGIILF
FVMYLITSGF SATTAESTKN AMCIFAPVAM AFGVQTMANA EASSLGITFG NVNEPYQNFR
FSTSLYYMAF DIVLYTLLGL YLEKVVPKDY GITEKWYFLV SPSYWRNKRS AGSVQTNLNI
DDAAYVEGAA HDAIEPVGME LKAQEATGEA LQIRRLRREF KVPGGTKVAV HGLDLTMYKN
QITCLLGHNG AGKTTLISML TGMIPASGGD ATFNGLSLRN DLSELRQSLG MCPQHDVLYA
ELTVEEHLIF YGRIKGFSGK ALTEEVADKI AEVGLTEKRH VASSELSGGM KRKLSLAIAL
LGDSKIVFLD EPTSGMDPYS RRSSWEIIMN NRMNRIVVLT THFMDEADIL GDRIAIMAEG
QLRCVGSSLF LKNRYGAGYN FALVRTETCD TAALIAFVQS HIPVAKVLSN VGTEMSFQLP
LDHAPSFAAM FADLEVQSSA LGVLSYGISV TTLEEVFIKV AEIGDEHQQH TLQPRNDAGP
LLSPAGYKIN TAEAPPSRLR MFGRHFVALF KKRFRTAKRD KKIVLFGAVL PVVFLILGMC
ILKFSSLSKN DTAMSINLQS YGSMTSVPVT CQGDAAWCAA FPAAYAAGKA SLLSVPTPAY
PTNNPTVFDI TYTNPAIAAN DTTGTCLATG YEVYQRGYGG AGASPVLGQY GGYVLQASSV
DNTYGYNVLV NTTAVHAAPN YKAAIDETLY QLFTQQPGIT LKVTSHPLPL TAMTKTLFTT
FMSFATSIFV VLAFAFFTAS IVPYLVNEKH HSHNSKHQQL VSGVSLPAFW LANFAWDMML
FMIPCVIGLV AIYLFDITPF TGNDCFGCAA NPFGAVITLF VLLGFALCSF CYCLSYLFSE
PASSQTYTIM TNIALGTVLM TVSIVLDVIE STKDINPSLK FIWRLSPLFC VGNALNQLSI
YTIRSTFGRT TKEVSSFSTD VIGYEIMYLA IEAVLFPILA IGIDYALSFP KIKAKLSKDP
VIVDAPVDID VDVQAEADRV NSGRADNDAV VMRNLRKVYK GGKVGVSNIA LALPKGECFG
YLGINGAGKT STMKMMTGDV LPTSGTATLG GFDILSQQIE VRRLMGYCPQ FDALMDLLTV
REHLELFAAI KGVPSGRIND TVAEKMTQMN LNDFEHKLAG TLSGGNKRKL SVAIAMIGAP
PIIFLDEPST GMDPVSRRFM WDVIADISTR SKESTILLTT HSMEECEALC TRVGIMVGGR
LRCLGSIQHL KHRFGDGLMM HIKLAHVPGD AIMDFVEHEF GATPTLSLED AQEACRRLGK
PQRSSCIAMD HATGYTLMES ITKNQYIRAR DFCTWWLTED RFEAFNAFLA TAMGAGHAQL
LERQNDVARF KLMSPTKLLL SPFFDARGLQ GRVPRRRVHG GADDIGADL
//
