ID   A0A067DMU6_CITSI        Unreviewed;       581 AA.
AC   A0A067DMU6;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Adenine/guanine permease AZG1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CISIN_1g008018mg {ECO:0000313|EMBL:KDO44304.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO44304.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO44304.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR   EMBL; KK785314; KDO44304.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067DMU6; -.
DR   STRING; 2711.A0A067DMU6; -.
DR   PaxDb; 2711-XP_006486207-1; -.
DR   eggNOG; ENOG502QQ5E; Eukaryota.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005345; F:purine nucleobase transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015853; P:adenine transport; IBA:GO_Central.
DR   GO; GO:0015854; P:guanine transport; IBA:GO_Central.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337:SF19; ADENINE_GUANINE PERMEASE AZG1; 1.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        128..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        293..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        375..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        452..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        476..497
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        509..537
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          560..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   581 AA;  61797 MW;  216EC532D1A746C6 CRC64;
     MEVEANSNSN SNPKPLTRLN ALVASSRVGK RFKLKERNTT FTTELRAGTA TFLTMAYILA
     VNASIIADSG GTCTVSDCVA LCSNPSVPLA NCTTSDPAYR VVQPDESCKF NPVNPGYQSC
     LEKLRKDLIV ATVASSLIGC VIMGAFANLP LALAPGMGTN AYFAYTVVGF HGSGNVSYRS
     ALTAVFMEGL IFLFISAIGF RSKLAKLVPK PVRISSSAGI GLFLAFIGLQ NNQGIGLIGY
     SSSTLVTLGA CPRSARAALA PVVTAANGTA SLIPGGTVSG DILCLRDRME SPTFWLGVVG
     FVIIAYCLVK NIKGAMIYGV VFVTVVSWFR NTKVTAFPDT DAGNSAHKYF KKVVDVHVIE
     STAGALSFKS MGKGYFWEAV VTFLYVDILD TTGTLYSMAR FAGFTDQNGD FEGQYFAFMS
     DAMSIVVGAL LGTSPVTTFI ESSTGIREGG RTGLTALTVA GYFFLALFFT PLLASIPAWA
     VGPPLILVGV LMMRSVVEIE WDDMRQAIPA FLTLILMPLT YSIAYGLIGG ICTYIVLHIW
     DWGHKSLVKI GVVKKKSSGV SGAPQQIREG DGNGKANEIE V
//