ID A0A067DV51_CITSI Unreviewed; 677 AA.
AC A0A067DV51;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=CISIN_1g005789mg {ECO:0000313|EMBL:KDO46884.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO46884.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO46884.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
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DR EMBL; KK785196; KDO46884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067DV51; -.
DR STRING; 2711.A0A067DV51; -.
DR PaxDb; 2711-XP_006478528-1; -.
DR eggNOG; KOG1979; Eukaryota.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0032389; C:MutLalpha complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IBA:GO_Central.
DR CDD; cd16926; HATPase_MutL-MLH-PMS-like; 1.
DR CDD; cd03483; MutL_Trans_MLH1; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032189; Mlh1_C.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF12; DNA MISMATCH REPAIR PROTEIN MLH1; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR Pfam; PF16413; Mlh1_C; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120}.
FT DOMAIN 230..353
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 355..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 531..569
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 361..389
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 677 AA; 75705 MW; 2D4B0ED4BFB576C1 CRC64;
MDTEEAWTPE AEAAAVKEPP KIHRLEESVV NRIAAGEVIQ RPVSAVKELV ENSLDADATS
INVVVKDGGL KLIQVSDDGH GIRYEDLPIL CERHTTSKLS KYEDLQSIKS MGFRGEALAS
MTYVGHVTVT TITKGHLHGY RVSYRDGVME SEPKACAAVK GTQIMVENLF YNMIARRKTL
QNSSDDYTKI VDLLSRMAIH HTNVSFSCRK HGAARADVHS IATSSRLDSI RTVYGVSVAS
NLVQLEASEY NDSSSFVFKM DGYVSNSNYV AKKTTMVLFV NDRLVECAPL KRAVEIVYAA
TFPKASKPFI YMSIVLPPEH VDVNVHPTKR EVSLLNQELI VEKIQSAVEL KLRQSNDSRT
YKEQTVESSP SSPYNPSKDL HLNPSGSKLQ KVPVNKMVRT DSSDPAGRLH AYVQSKPHTS
VASGPNLSAV RSSVRQRRNL NETADLTSIQ ELIDDVDRNC HSGLLDIVRH CSFIGMADDV
YALLQHNTHM YLANVVSLSK ELMYQLVLRR FAHFNAIQLS DPAPLSELLM LALKEEDLDV
ENSENDDLKE KIAEMNTELL KQKAEMLEEY FCVKIDTRGN LSRLPIILDQ YTPDMDRIPE
FVLCLGNDVD WEDEKCCFQA IAAALGNFYA MHPPLLPNPS GEGLQCYKKR KPLKNPVDIE
RYPNDAGMAI HPREVIV
//
