ID   A0A067DVQ3_CITSI        Unreviewed;       762 AA.
AC   A0A067DVQ3;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=CISIN_1g0014791mg {ECO:0000313|EMBL:KDO45640.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO45640.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO45640.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C19 family.
CC       {ECO:0000256|ARBA:ARBA00009085}.
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DR   EMBL; KK785242; KDO45638.1; -; Genomic_DNA.
DR   EMBL; KK785242; KDO45639.1; -; Genomic_DNA.
DR   EMBL; KK785242; KDO45640.1; -; Genomic_DNA.
DR   PaxDb; 2711-XP_006477929-1; -.
DR   eggNOG; KOG1865; Eukaryota.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd02661; Peptidase_C19E; 1.
DR   Gene3D; 6.10.140.2220; -; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   InterPro; IPR002893; Znf_MYND.
DR   PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   PANTHER; PTHR24006:SF685; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15; 1.
DR   Pfam; PF00443; UCH; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR   PROSITE; PS00972; USP_1; 1.
DR   PROSITE; PS50235; USP_3; 1.
DR   PROSITE; PS01360; ZF_MYND_1; 1.
DR   PROSITE; PS50865; ZF_MYND_2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00134}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          103..140
FT                   /note="MYND-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50865"
FT   DOMAIN          478..762
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
FT   REGION          253..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..307
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         762
FT                   /evidence="ECO:0000313|EMBL:KDO45640.1"
SQ   SEQUENCE   762 AA;  85434 MW;  CAFF891879A31B23 CRC64;
     MLEPREADVP VLFLVLVVLP LVAYVLLGKW SEAAKKRERI SLLAQLAAEE ALRVEAVPSV
     SVSPLVPTSI NEFHVSTSKN EFNVPTLKNE FPASTSKNGF QLCARCFAPA TTRCSRCKSV
     RYCSGKCQII HWRQVHKQEC QQLEKTSSSS PSLAGSVDDS VNESLNLQLS GYNNKQGGMG
     EAPPDGVIHP SMSRCASSSM DCSTLENSQT SMMERTVDKR VYRKSKKDLL RRDVATMFDS
     HDEILRSCTS DPISSNNFSS KEAPIRHKSR TGASAVSSEE SQRNLNLNSS DGCAYGQGTT
     GSTTYDSNGY RSRHWNISEP RNSCESSSSS NSAKYGTYTR ENELDFTSNG KKFLNESIEL
     NGYCEMKAMN PMGTKNCKSA KSCTKVVGDQ SCLEKERKGP IADESKAARV RDTIPAQGSN
     VVSKMGIMKM MGLRKSTKLR QDSSELWHDQ HRKLKMLFPY EEFLKLFQYE VIDLLSPRGL
     LNCGNSCYAN AVLQCLTCTK PLVIYLLRRS HSSACCGKDW CLMCELEQHV MMLRESAGPL
     SPGRILSHMR SISCQIGDGS QEDAHEFLRL LVASMQSICL ERHGGESKVD PRLQETTFIQ
     HTFGGRLWSK VKCLRCSHES ERYENIMDLT LEIYGWVESL EDALTQFTSP EDLDGENMYK
     CARCATYVRA RKQLSIHEAP NILTIVLKRF QEGRYGKINK CITFPEMLDM MPFMTGTGDT
     PPLYMLYSVV VHLDTQNASF SGHYVSYIKD MQGTWFRIDD TQ
//