ID   A0A067DWX4_CITSI        Unreviewed;      1264 AA.
AC   A0A067DWX4;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=5-oxoprolinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CISIN_1g000831mg {ECO:0000313|EMBL:KDO47328.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO47328.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO47328.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KK785180; KDO47328.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067DWX4; -.
DR   STRING; 2711.A0A067DWX4; -.
DR   PaxDb; 2711-XP_006478689-1; -.
DR   eggNOG; KOG1939; Eukaryota.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IBA:GO_Central.
DR   GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120}.
FT   DOMAIN          10..212
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          235..534
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          558..711
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          735..1263
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1264 AA;  137698 MW;  A788802207765FDB CRC64;
     MGSVKEEKLR FCIDRGGTFT DVYAEIPGQL EGQVLKLLSV DPTNYDDAPV EGIRRILEEY
     TGEKIPRTSK IPTDKIEWIR MGTTVATNAL LERKGERIAL CVTRGFKDLL QIGNQARPQI
     FDLTVSTPSN LYEEVIEVDE RVELVLENEK ENQESLVKGV SGELVRVVKP VNEKTLEPLL
     KGLLEKGISC LAVVLMHSYT FPQHEMAVEK LALGLGFRHV SLSSALTPMV RAVPRGLTAS
     VDAYLTPVIK EYLSGFMSKF DEGLAKVNVL FMQSDGGLAP ESRFSGHKAV LSGPAGGVVG
     YSQTLFGLET EKPLIGFDMG GTSTDVSRYA GSYEQVLETQ IAGAIIQAPQ LDINTVAAGG
     GSNLMFQLGA FRVGPESVGA HPGPVCYRKG GDLAVTDANL ILGFVIPDYF PSIFGPNEDQ
     PLDINATREK FQKLASEINS YRKSQDPSVK DMTVEDIALG FVNVANETMC RPIRQLTEMK
     GHETRNHALA CFGGAGPQHA CAIARSLGMR EVLIHRFCGI LSAYGMGLAD VVEEAQEPYS
     AVYGPESVLE VSRREGILSK QVKQKLQEQG FREESITTET YLNLRYEGTD TAIMVKKRIA
     EDGSGCGYAV DFEKLFQQEY GFKLQNRNIL VCDVRVRGIG VTNILKPQAI EPTSGTPKVE
     GHYKVFFNGW HDAPLYKLEN LGYGHVMPGP AIIMNGNSTV IVEPNCKAVI TKYGNIKIEI
     ESISSTINIA ENIADVVQLS IFNHRFMGIA EQMGRTLQRT SISTNIKERL DFSCALFGPD
     GGLVANAPHV PVHLGAMSST VRWQLKYWRH NLNEGDVLVS NHPCAGGSHL PDITVITPVF
     DNGKLVFFVA SRGHHAEIGG ITPGSMPPFS KSIWEEGAAI KAFKLVEKGI FQEEGITKLL
     LDPSSEDSAH KIPGTRRLQD NLSDLRAQVA ANQRGISLIK ELIEQYGLKT VQAYMTYVQL
     NAEEAVREML KSVAAKVSSE SAKDGERNFV TIEEEDYMDD GSVIHLKLTI DSDKGEAFFD
     FSGTSSEVLG NWNAPEAVTA AAVIYCLRCL VDVEIPLNQG CLAPVKIHIP PGSFLSPSEK
     AAVVGGNVLT SQRITDVVLT AFQACACSQG CMNNLTFGDS TFGYYETIGG GSGAGPTWDG
     TSGVQCHMTN TRMTDPEIFE QRYPVFLHKF GLREKSGGAG LHRGGDGLVR EIEFRRPVVV
     SILSERRVHA PRGLKGGKDG ARGANYLITK DKRKVYLGGK NTVQVQPGEI LQILTPAGGG
     WGSL
//