ID   A0A067E2L8_CITSI        Unreviewed;       538 AA.
AC   A0A067E2L8;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KDO49313.1};
GN   ORFNames=CISIN_1g009276mg {ECO:0000313|EMBL:KDO49313.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO49313.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO49313.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974}.
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DR   EMBL; KK785114; KDO49313.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067E2L8; -.
DR   STRING; 2711.A0A067E2L8; -.
DR   PaxDb; 2711-XP_006493005-1; -.
DR   eggNOG; KOG2466; Eukaryota.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015851; P:nucleobase transport; IBA:GO_Central.
DR   CDD; cd11485; SLC-NCS1sbd_YbbW-like; 1.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR   PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR   PANTHER; PTHR30618:SF0; PURINE-URACIL PERMEASE NCS1; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        100..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        154..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        196..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        227..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        307..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        350..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        412..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        457..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        503..521
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   538 AA;  58796 MW;  FD3666AB7B4F1FFB CRC64;
     MVSKCFSINL HHHLQLSLPA AISPKPNRPS PWQLANPSIF SATKITTFHK FCGSLTRAMP
     LSSTEFNDDL EPHLTLRNED LKPSTINERT FSCLVDLGMA WWQGIATVVA ANVILLVPLV
     LTGHPGTKYG IPFPVLARSS FGIKGAHIPT LLRALVGCGW YGIETWIGGE AVFLLLPKFI
     KQSSILSQSL PWLGTSPLEF ACFIAFWLAQ LAIVWKGIEG IRELEKYSAP ILIILTSSFL
     FWAYVNAGGF GHMLSKSSKL SSSEFWSLFF PSLTANISFW ATVALNIPDF TRYAKSQNDQ
     ILGQAGLPIF MGAFTFVGLA ITCSTQVIFG RVISSPIQLL DQIGGITTRI LGIIGISLAT
     ITTNIAANVV APANALVNLR PSIFTFRKGA ILTALLGIAF QPWRLLKSSE SFVYTWLVGY
     SALLGPIGGI ILADYYLIQG AKLSIKYLYS LNPNGAYYYS GGYNLVAIMA LSIGILPVIP
     GFLQKVGLVV TIPNSFVVIY NNAWFFSFFL AGFVYWVLSL LRGKQNSPPF EDLLPSAT
//