ID   A0A067EI56_CITSI        Unreviewed;       698 AA.
AC   A0A067EI56;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=RelA/SpoT domain-containing protein {ECO:0000259|SMART:SM00954};
GN   ORFNames=CISIN_1g003224mg {ECO:0000313|EMBL:KDO50601.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO50601.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO50601.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK785076; KDO50601.1; -; Genomic_DNA.
DR   RefSeq; XP_006478904.1; XM_006478841.2.
DR   AlphaFoldDB; A0A067EI56; -.
DR   OrthoDB; 1396at2759; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0008728; F:GTP diphosphokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   CDD; cd05399; NT_Rel-Spo_like; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR007685; RelA_SpoT.
DR   InterPro; IPR004095; TGS.
DR   InterPro; IPR012676; TGS-like.
DR   PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR   PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR   Pfam; PF13328; HD_4; 1.
DR   Pfam; PF04607; RelA_SpoT; 1.
DR   Pfam; PF02824; TGS; 1.
DR   SMART; SM00954; RelA_SpoT; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   SUPFAM; SSF81271; TGS-like; 1.
DR   PROSITE; PS50889; S4; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT   DOMAIN          284..403
FT                   /note="RelA/SpoT"
FT                   /evidence="ECO:0000259|SMART:SM00954"
SQ   SEQUENCE   698 AA;  77811 MW;  FA3A52AD63DF6B0A CRC64;
     MLIPSSGKRA VDTVVAGILH DVVDDACESL GSIEEEFGDE VAKLVAGVSR LSYINQLLRR
     HRRINVNQGT LGHEEANDLR VMLLGMVDDP RVVLIKLADR LHNMRTIYAL PPAKARAVAQ
     ETLLIWCSLA SRLGLWALKA ELEDLCFAVL QPQIFRKMRA DLASMWSPRN RVGYSRRITT
     IVSSPPLDER TASDDESFTT FDEHVLSMKD LLEAVVPFDI LSDRRKRTKF LHDLAKSSEA
     QKKAKVVQDA GIALTSLVAC EEALEKELLI STSYIPGMEV TLSSRLKSLY SIFSKMRRKD
     VGIHKVYDAR ALRVVVGDKN GTLHGPAIQC CYSLLDIVHR LWIPIDGEFD DYIVNPKPSG
     YQSLHTAVQG PDGSALEVQI RTQKMHEYAE HGLAAHWLYK ETGNKLQSIS SMDESDIEAS
     SSLSKDTDDH NPLDTDLFQK YSSLKMGHPV IRVEGSNLLA AVIIRVEKGG RELLVAVSFG
     LAASEVVADR RPSFQIKCWE AYARLYKKAS DEWWCQPGHG DWCTCLEKYT LCRDGMYHKQ
     DQFGRLLPTF IQITHLTEEE ESEYWAVVSA VFEGKPVDSV VSRRSSDSVA PTSMEASINN
     KVRLLRTMLR WEEQLRSEAS LRQSKLGGKA NGNPDSVVPG EVVIVCWPNG EIMRLRSGST
     AADAAMKVGL EGKLVLVNGQ LVLPNTELKD GDIVEVRV
//