ID   A0A067ERH7_CITSI        Unreviewed;       605 AA.
AC   A0A067ERH7;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=Beta-galactosidase {ECO:0000256|ARBA:ARBA00012756, ECO:0000256|RuleBase:RU000675};
DE            EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756, ECO:0000256|RuleBase:RU000675};
GN   ORFNames=CISIN_1g004219mg {ECO:0000313|EMBL:KDO57769.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO57769.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO57769.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC         in beta-D-galactosides.; EC=3.2.1.23;
CC         Evidence={ECO:0000256|ARBA:ARBA00001412,
CC         ECO:0000256|RuleBase:RU000675};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC       {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR   EMBL; KK784958; KDO57768.1; -; Genomic_DNA.
DR   EMBL; KK784958; KDO57769.1; -; Genomic_DNA.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR048913; BetaGal_gal-bd.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR041392; GHD.
DR   InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR   InterPro; IPR019801; Glyco_hydro_35_CS.
DR   InterPro; IPR001944; Glycoside_Hdrlase_35.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR23421:SF63; BETA-GALACTOSIDASE 12; 1.
DR   PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR   Pfam; PF21467; BetaGal_gal-bd; 1.
DR   Pfam; PF17834; GHD; 1.
DR   Pfam; PF01301; Glyco_hydro_35; 1.
DR   PRINTS; PR00742; GLHYDRLASE35.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120}.
FT   DOMAIN          46..349
FT                   /note="Glycoside hydrolase 35 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01301"
FT   DOMAIN          372..428
FT                   /note="Beta-galactosidase beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17834"
FT   DOMAIN          480..547
FT                   /note="Beta-galactosidase galactose-binding"
FT                   /evidence="ECO:0000259|Pfam:PF21467"
SQ   SEQUENCE   605 AA;  67743 MW;  944A1756A4DB77C9 CRC64;
     MGEKQVLVKW KMLGANVKVL MLVLLSFCSW EISFVKASVS YDHKAVIING QKRILISGSI
     HYPRSTPEMW PDLIQKAKDG GLDVIQTYVF WNGHEPTQGN YYFQDRYDLV RFIKLVQQAG
     LYVHLRIGPY VCAEWNYGGF PVWLKYVPGI EFRTDNGPFK AAMHKFTEKI VSMMKAEKLF
     QTQGGPIILS QIENEFGPVE WDIGAPGKAY AKWAAQMAVG LNTGVPWVMC KQDDAPDPVI
     NTCNGFYCEK FVPNQNYKPK MWTEAWTGWF TEFGSAVPTR PAEDLVFSVA RFIQSGGSFI
     NYYMYHGGTN FGRTSGGFVA TSYDYDAPID EYGLLNEPKW GHLRDLHKAI KLCEPALVSV
     DPTVKSLGKN QEAHVFNSKS GKCAAFLANY DTTFSAKVSF GNAQYDLPPW SISVLPDCKT
     AVFNTARVGV QSSQKKFVPV INAFSWQSYI EETASSTDDN TFTKDGLWEQ VYLTADASDY
     LWYMTDVNID SNEGFLKNGQ DPLLTIWSAG HALQVFINGQ LSGTVYGSLE NPKLTFSKNV
     KLRPGVNKIS LLSTSVGLPN VGTHFEKWNA GVLGPVTLKG LNEGTRDISK QKWTYKVCLS
     LDILR
//