ID A0A067EXV6_CITSI Unreviewed; 523 AA.
AC A0A067EXV6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=4-coumarate--CoA ligase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CISIN_1g009867mg {ECO:0000313|EMBL:KDO59994.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO59994.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO59994.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; KK784934; KDO59994.1; -; Genomic_DNA.
DR RefSeq; XP_006490394.1; XM_006490331.2.
DR RefSeq; XP_015389521.1; XM_015534035.1.
DR RefSeq; XP_015389522.1; XM_015534036.1.
DR AlphaFoldDB; A0A067EXV6; -.
DR STRING; 2711.A0A067EXV6; -.
DR PaxDb; 2711-XP_006490394-1; -.
DR GeneID; 102612322; -.
DR KEGG; cit:102612322; -.
DR eggNOG; KOG1176; Eukaryota.
DR OrthoDB; 1404660at2759; -.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0031956; F:medium-chain fatty acid-CoA ligase activity; IBA:GO_Central.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR CDD; cd05926; FACL_fum10p_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR045310; Pcs60-like.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF34; OXALATE--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000027120}.
FT DOMAIN 15..373
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 424..499
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 523 AA; 56163 MW; D3DBC3FAD1E3B0A4 CRC64;
MEGVTLIGLL NQVIDQFSSK RALSVSGKFD LTYSRIHELV ERAASRLVAA GINAGDVVAL
TFPNTVEFVI MFLAVIRARA TAAPLNAAYT PDEFEFYLSD SESKLLLTPA EGNAAAQAAA
SKLNISHATA TLLDADSELT LSLAHSESDT NAISKLTNDP SDVALFLHTS GTTSRPKGVP
LTQNNLAASV SNIKSVYKLT ESDSTVIVLP LFHVHGMLAG LLSSFAAGAA VTLPAAGRFS
ASTFWQDMIK YNATWYTAVP TIHQIVLDRH VAKPEPVYPK LRFIRSCSAS LAPVILSRLE
EAFGAPVLEA YAMTEATHLM SSNPLPEDGP HKPGSVGRPV GQEIAILDEI GVPQEGGAKG
EVCIRGPNVT KGYKNNPEAN KSAFLFGWFH TGDIGYFDSD GYLHLVGRIK ELINRGGEKI
SPIEVDAVLL SHPDIAQAVA FGVPDDKYGE EINCAIIPRE GSNIDEEEVL RFCKKNVAAF
KVPKRVFITN ELPKTASGKI QRRIVSEHFL AQVSAAKVPK FGA
//
