ID A0A067F0U1_CITSI Unreviewed; 492 AA.
AC A0A067F0U1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=CNNM transmembrane domain-containing protein {ECO:0000259|PROSITE:PS51846};
GN ORFNames=CISIN_1g011147mg {ECO:0000313|EMBL:KDO56811.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO56811.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO56811.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK784969; KDO56811.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067F0U1; -.
DR STRING; 2711.A0A067F0U1; -.
DR PaxDb; 2711-XP_006490692-1; -.
DR eggNOG; KOG2118; Eukaryota.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0030026; P:intracellular manganese ion homeostasis; IBA:GO_Central.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR PANTHER; PTHR12064:SF36; DOMAIN-CONTAINING PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU01193, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU01193,
KW ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU01193,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..192
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT REGION 422..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 53924 MW; DA2B0F783AA5058A CRC64;
MAANDVPCCE PMFWVYLVIC VGLVSFAGLM SGLTLGLMSL SLVDLEVLMR AGQPQDRKNA
EKILPIVKNQ HLLLCTLLIG NAMAMEALPI FLDALLPAWA SIVISVTLIL AFGEIIPQAV
CSRYGLSVGA KLSVLVRLIV IVLFPIAYPI SKLLDWLLGK RHSALLRRAE LKTLVDMHGN
EAGKGGELTH DETTIITGAL DMTQKTAKDA MTAMSKIFSL DINSRLDEKT MGLIISNGHS
RVPIYVGTPT NIIGAILGHS HMAVVVKCKN DSKEIAEMEK SKAPMQHDIN INSNLKQRQG
ELKGNVQNEQ FNAYMNSPSV ISSDIDIQSS MAKSADLHLC LKKWERQDVK ISKEELESLP
SVDEEVIGII TLEDVMEELL QEEILDETDD YVDVHRKIKI NMLESQKSPS PGAAFVSRLR
RTPMDSPIPS HHDQTPVSSY NHSPIIHSPA LPYIQSPFIR PTLSASPGKS LPTSLATLTE
TTGHSPPAHR VT
//
