ID   A0A067F379_CITSI        Unreviewed;      1020 AA.
AC   A0A067F379;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Ribonuclease {ECO:0000256|PIRNR:PIRNR017179};
GN   ORFNames=CISIN_1g001725mg {ECO:0000313|EMBL:KDO57651.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO57651.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO57651.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cytoprotective ribonuclease (RNase) required for resistance
CC       to abiotic stresses, acting as a positive regulator of mRNA decapping
CC       during stress. {ECO:0000256|PIRNR:PIRNR017179}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR017179}.
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DR   EMBL; KK784959; KDO57651.1; -; Genomic_DNA.
DR   EMBL; KK784959; KDO57652.1; -; Genomic_DNA.
DR   RefSeq; XP_006485058.1; XM_006484995.2.
DR   STRING; 2711.A0A067F379; -.
DR   PaxDb; 2711-XP_006485058-1; -.
DR   GeneID; 102617109; -.
DR   KEGG; cit:102617109; -.
DR   eggNOG; KOG2039; Eukaryota.
DR   OrthoDB; 375531at2759; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016442; C:RISC complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004518; F:nuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0006402; P:mRNA catabolic process; IBA:GO_Central.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:InterPro.
DR   CDD; cd20443; Tudor_AtTudor1-like; 1.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 2.40.50.90; -; 5.
DR   InterPro; IPR016685; Silence_cplx_Nase-comp_TudorSN.
DR   InterPro; IPR035437; SNase_OB-fold_sf.
DR   InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR   InterPro; IPR002999; Tudor.
DR   InterPro; IPR047395; Tudor_AtTudor1-like.
DR   PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR   PANTHER; PTHR12302:SF2; STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00565; SNase; 4.
DR   Pfam; PF00567; TUDOR; 1.
DR   PIRSF; PIRSF017179; RISC-Tudor-SN; 1.
DR   SMART; SM00318; SNc; 4.
DR   SMART; SM00333; TUDOR; 1.
DR   SUPFAM; SSF50199; Staphylococcal nuclease; 5.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR   PROSITE; PS50830; TNASE_3; 4.
DR   PROSITE; PS50304; TUDOR; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR017179};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          10..151
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          186..364
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          378..586
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          616..743
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          809..874
FT                   /note="Tudor"
FT                   /evidence="ECO:0000259|PROSITE:PS50304"
FT   REGION          470..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          998..1020
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1020 AA;  111314 MW;  E9461387E588F321 CRC64;
     MATPAAAGGG WYRARVKAVP SGDSLVITAL SNPNPGPPRE KTLTLSSIIT PRLARRGGLD
     EPFAWDSREF LRKLCIGKEV TFRVDYAVPN IGREFGTVIL GDKNVAMLVV SEGWAKVKEQ
     GSQKGEASPF LAELLRLEEQ AKLQGLGRWS KVPGAAEASI RNLPPSAIGD SSNFNAMALL
     DANKGRPMQG IVEQARDGST LRVYLLPEFQ FVQVFVAGIQ APAVARRPAA IVDTDTEETN
     GDVSAAEAVA PLNSAQRLAA STASAGQQST DEPFALDAKY FTEMRVLNRE VRIVLEGVDK
     FKNLIGSVFY PDGETAKDLA MELVENGLAK YIEWSANMME EDAKRRLKAA DLQAKKTRLR
     MWTNYVPPQS NSKAIHDQNF TGKVVEVVSG DCIIVADDSI PYGNALAERR VNLSSIRCPK
     IGNPRKDEKP AAYAREAREF LRTRLIGRQV NVQMEYSRKV VVEAAPVAAG AKGPAGTKGP
     AGTKGQAAAK GPAGEESVGA TETRIIDFGS IFLLSPIKGE GDDASAVAQS NAAGQPAGVN
     VAELVVSRGL GNVINHRDFE ERSNYYDALL AAEARAKAGK KGCYSSKEPP VMHIQDLTMA
     PVKKARDFLP FLQRSRRIPA VVEYVLSGHR FKVLIPKETC SIAFSFSGVR CPGRNERYSN
     EALLLMRQKI LQRDVEIEVE TVDRTGTFLG SLWESRTNVA VILLEAGLAK LQTSFGSDRI
     PDSHLLEQAE KSAKSQKLKI WENYVEGEEV SNGAAVEGKQ KEVLKVVVTE ILGGGKFYVQ
     QVGDQKVASV QQQLASLNLQ EAPVIGAFNP KKGEIVLAQF SADNSWNRAM IVNAPREKVE
     SVNDKFEVFY IDYGNQELVP YNKLRPIDPS LSSTPPLAQL CSLAYIKIPA LEDEYGPEAA
     EFLNEHTYNS SNEFRALVEE RDSSGGKLKG QGTGTLLHVT LVAVDAEISI NTLMVQEGLA
     RVERRKRWGS RDRQAALENL EKFQEEAKTA RIGMWQYGDI QSDDEDPLPS AVRKVAGGRR
//