ID   A0A067F5F6_CITSI        Unreviewed;       378 AA.
AC   A0A067F5F6;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE            EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN   ORFNames=CISIN_1g013955mg {ECO:0000313|EMBL:KDO62624.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO62624.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO62624.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC         Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000032,
CC         ECO:0000256|RuleBase:RU361203};
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC         Evidence={ECO:0000256|ARBA:ARBA00001962};
CC   -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC       acid phosphatase family. {ECO:0000256|ARBA:ARBA00008723,
CC       ECO:0000256|RuleBase:RU361203}.
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DR   EMBL; KK784918; KDO62624.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067F5F6; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd00839; MPP_PAPs; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR041792; MPP_PAP.
DR   InterPro; IPR039331; PPA-like.
DR   InterPro; IPR008963; Purple_acid_Pase-like_N.
DR   InterPro; IPR015914; Purple_acid_Pase_N.
DR   PANTHER; PTHR22953; ACID PHOSPHATASE RELATED; 1.
DR   PANTHER; PTHR22953:SF153; PURPLE ACID PHOSPHATASE; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   Pfam; PF16656; Pur_ac_phosph_N; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR   SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361203};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|RuleBase:RU361203"
FT   CHAIN           21..378
FT                   /note="Purple acid phosphatase"
FT                   /evidence="ECO:0000256|RuleBase:RU361203"
FT                   /id="PRO_5005103303"
FT   DOMAIN          43..130
FT                   /note="Purple acid phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16656"
FT   DOMAIN          138..328
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
SQ   SEQUENCE   378 AA;  42855 MW;  F01037C02ABCA3FC CRC64;
     MELKFVLTAF VFISATVTTA EYIRPQPRRT LEFPWDPKPS SHPQQVHISL AGDSHMRVTW
     ITDDESSPSV VEYGTSPGGY NCGAEGESTS YRYLFYRSGK IHHTVIGPLE HDTVYFYRCG
     RQGPEFEFKT PPAQFPITFA VAGDLGQTGW TKSTLDHIGQ CKYDVHLLPG DLSYADYMQH
     RWDTFGELVQ PLASARPWMV TQGNHEKESI PLIMDAFQSY NARWKMPFEE SGSNSNLYYS
     FDVAGAHLIM LGSYADYDEY SDQYRWLKDD LSKVDRKKTP WLLVLLHVPW YNSNEAHQGE
     GDGMMAIMEP LLYAASVDLV LAGHVHAYER SIRVNNGKPD PCGAVYITIG DGGNKEGLAR
     KYVLTYRNIF ELSNSNKK
//