ID A0A067G4S9_CITSI Unreviewed; 740 AA.
AC A0A067G4S9;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=CISIN_1g004645mg {ECO:0000313|EMBL:KDO74608.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO74608.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO74608.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; KK784883; KDO74608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067G4S9; -.
DR STRING; 2711.A0A067G4S9; -.
DR PaxDb; 2711-XP_006489378-1; -.
DR eggNOG; KOG0584; Eukaryota.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0035556; P:intracellular signal transduction; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13983; STKc_WNK; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR024678; Kinase_OSR1/WNK_CCT.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR13902; SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED; 1.
DR PANTHER; PTHR13902:SF179; SERINE_THREONINE-PROTEIN KINASE WNK2; 1.
DR Pfam; PF12202; OSR1_C; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 25..282
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 638..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 740 AA; 84461 MW; 00476274F0B4C8EA CRC64;
MNGVSSPEES DSSEFVEVDP TGRYGRYNEI LGKGASKTVY RAFDEYEGIE VAWNQVKLYD
FLQSPEELER LYCEIHLLKT LKHRNIMKFY TSWVDTANRN INFVTEMFTS GTLRQYRLKH
RRVNIRAVKH WCRQILSGLL YLHSRDPPVI HRDLKCDNIF VNGNQGEVKI GDLGLAAILR
KSHAARCVGT PEFMAPEVYE EEYNELVDIY SFGMCILEMV TFDYPYSECT HPAQIYKKVI
SGKKPEALFK VEDPEVRQFI EKCLATVSSR LSARELLTDP FLQIDDYDSD LRMIQYQTDY
DEISPLLRQS LYGIYHSNSS SNNGCGHYIG YDTENGLDYH PHEFQESEID LFTCQEDEHL
TNFDISIKGK RREDDGIFLR LRIADKEGRI RNIYFPFDIQ TDTALSVATE MVSELDITDQ
DVTKIAEIID SEIASLVPEW KRGMAMEESP HRSSFCHNCA SNGCLPDYIL SDGSGAKNLQ
VLQCSKDGCA AIHGRFEEIT YQVDGAEQCA PEGADQAASP QSAVVHYADI WAQHEGQVLS
SQGSRDIHCD EEHKTLNQSS YGAEEKIINM DSQSKCHERN CFSMNSAMDY GLLDDYENEI
RQELRWLKAK YQIQLRELRD QQLGVKYKSS SLTLITDDKT RASDDKVSPS SVLPEPESNR
PPQRTIAHRP TKHLTSCLPI GDEKKCGNVA NQRVHSFEQM NWPCSPEQMV TAKSYYTPLL
PHSLHRATSL PVDSVDVSSQ
//
