ID A0A067G7X4_CITSI Unreviewed; 396 AA.
AC A0A067G7X4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Auxin efflux carrier {ECO:0008006|Google:ProtNLM};
GN ORFNames=CISIN_1g013221mg {ECO:0000313|EMBL:KDO71531.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO71531.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO71531.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cellular auxin homeostasis by regulating auxin
CC metabolism. Regulates intracellular auxin accumulation at the
CC endoplasmic reticulum and thus auxin availability for nuclear auxin
CC signaling. {ECO:0000256|ARBA:ARBA00025100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
CC {ECO:0000256|ARBA:ARBA00025752}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK784889; KDO71531.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067G7X4; -.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0080162; P:endoplasmic reticulum to cytosol auxin transport; IEA:InterPro.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR InterPro; IPR045033; PILS1/3/4/5/7.
DR PANTHER; PTHR31651:SF3; PROTEIN PIN-LIKES 7; 1.
DR PANTHER; PTHR31651; TRANSPORTER; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 396 AA; 43454 MW; 8E26F0800F076272 CRC64;
MGFWTFFEVA SMPIVQVLLI SVLGALMATQ YWNLLTADAR RSLNKMVFTV FTPSLMFASL
AKTVTLEEII SWWFMPVNVA MTFLIGGILG WIVVKLLRPK PHLEGLVIAT CASGNLGNLL
LIIVPAICHE QGSPFGNRDV CSSVGLSYKA LAQAAEPEEV PKEVNKDFDA NAQTQLLRGT
TDDQEDVSVL VASTKSSSDP ECQIIVPQAS HLQTRKESFW KRSLEFLHQL LEELLAPPTL
AAIVGFIFGA VVWLRNLIIG DSAPLRVIQD SIEILGDGTI PCITLILGGN LIQGLRSSTL
KPLIIIAVVC VRYIALPFIG VWVVKAAAAL GFLPSDPLYH YVLMVQFTLP PAMNIGTMTQ
LFDVAQEECS VLFLWTYLVA ALALTGWSMV YMWILS
//
