ID A0A067GKH6_CITSI Unreviewed; 538 AA.
AC A0A067GKH6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CISIN_1g009299mg {ECO:0000313|EMBL:KDO80144.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO80144.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO80144.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KK784877; KDO80144.1; -; Genomic_DNA.
DR RefSeq; XP_006475901.1; XM_006475838.2.
DR AlphaFoldDB; A0A067GKH6; -.
DR STRING; 2711.A0A067GKH6; -.
DR PaxDb; 2711-XP_006475901-1; -.
DR GeneID; 102619882; -.
DR KEGG; cit:102619882; -.
DR eggNOG; KOG0158; Eukaryota.
DR OrthoDB; 1611592at2759; -.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24301; THROMBOXANE-A SYNTHASE; 1.
DR PANTHER; PTHR24301:SF2; THROMBOXANE-A SYNTHASE; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 538 AA; 60548 MW; 47B1E6EA421A6891 CRC64;
MALVSEILER FLMNREWFFT SNLGGSMIFT VLAILAGVLG YLYGPYWKVR RVPGPPAIPL
VGHIPLMAKY GPDVFSILAK RYGPIFRFHM GRQPLIIVAD AELCREVGIK KFKDIPNRSI
PSPIAASPLH QKGLFFTKNE RWSTMRNTIL SVYQPSHLAS LVPTMQSFIE SATQNLDSTE
DITFSDLSLK MATDVIGQAA FGVNFGLSKP QPISDSVTSV DTPANASEVS DFINQHIYST
TQLKMDLSGS LSIILGLLFP IIQEPFRQIL KRIPGTMDWK FARTNKNLSG RLEEIVSKRM
EETNTSSKDF LSLILKARES ETASKNIFTP DYISAVTYEH LLAGSATTAF TLSSVVYLVA
GHPEVEKKVL AEIDAFGPHD QMPTAHDLQH KFPYLNQVIK EAMRVYLVSP LVARETSKEV
KIGGYHLPKG TWVWLALGVL AKDPKNFPEP CKFKPERFDP NCEEEKRRHP YAFIPFGIGP
RACIGQKFSL QEIKLSLIQL YRKCVFRHSP NMEKPLELEY GIVLNFKHGV KLTVKNRK
//
