ID   A0A067GPY1_CITSI        Unreviewed;       367 AA.
AC   A0A067GPY1;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Chalcone synthase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CISIN_1g016111mg {ECO:0000313|EMBL:KDO80720.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO80720.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO80720.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC       ECO:0000256|RuleBase:RU003633}.
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DR   EMBL; KK784876; KDO80720.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067GPY1; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877:SF56; CHALCONE SYNTHASE; 1.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 2.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Transferase {ECO:0000256|RuleBase:RU003633}.
FT   DOMAIN          5..183
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          211..361
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        164
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ   SEQUENCE   367 AA;  40114 MW;  9D37D1BD76114691 CRC64;
     MEKVKDGKNQ QQGGGLATIL AIGTANPPNC IYQADYPDYY FRVTNSDHMT LLKQKFKRIC
     EKSNVKKRYF HVTEDILKKN PNICAYDGSS LDSRQDILVR EVPKLGEEAA TKAIKEWGQS
     KSQITHLIFC SLVGVDMPGA DYQLTKMLGL NPSVKRVMLY FQGCYIGATA IRMAKDFAEN
     NPGQALFGDG AAALIIGANP DTTLSEKPLF QIVSGAQTIL PGSDSDVAGQ FREMGLTVHL
     SKNVATVVSE NIEKCLDEAF SPFGIKDWNS LFWIVQPGGP AIVNQIEAKL GLKQQKLSAT
     RHVLSEYGNM GGVSVFFILD EIRRKSAEEG KVTTGEGLEW GVMFGIGAGV TVDTVVLRSF
     PFPTVTT
//