ID   A0A067GX22_CITSI        Unreviewed;       300 AA.
AC   A0A067GX22;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Vacuolar processing enzyme {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CISIN_1g011066mg {ECO:0000313|EMBL:KDO80012.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO80012.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO80012.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C13 family.
CC       {ECO:0000256|ARBA:ARBA00009941}.
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DR   EMBL; KK784877; KDO80012.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067GX22; -.
DR   MEROPS; C13.002; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0051603; P:proteolysis involved in protein catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR043577; AE.
DR   InterPro; IPR001096; Peptidase_C13.
DR   PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR12000:SF42; LEGUMAIN; 1.
DR   Pfam; PF01650; Peptidase_C13; 1.
DR   PIRSF; PIRSF500139; AE; 1.
DR   PIRSF; PIRSF019663; Legumain; 1.
DR   PRINTS; PR00776; HEMOGLOBNASE.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..300
FT                   /note="Vacuolar processing enzyme"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001642330"
FT   ACT_SITE        178
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT   ACT_SITE        220
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ   SEQUENCE   300 AA;  32786 MW;  2838615226621FF7 CRC64;
     MTRLASGVLI TLLVALAGIA DGSRDIAGDI LKLPSEAYRF FHNGGGGAKV NDDDDSVGTR
     WAVLLAGSNG FWNYRHQADI CHAYQLLRKG GLKDENIIVF MYDDIAFNEE NPRPGVIINH
     PHGDDVYKGV PKDYTGEDVT VENFFAVILG NKTALTGGSG KVVDSGPNDH IFIFYSDHGG
     PGVLGMPTSR YIYADELIDV LKKKHASGNY KSLVFYLEAC ESGSIFEGLL PEGLNIYATT
     ASNAEESSWG TYCPGEIPGP PPEYSTCLGD LYSIAWMEDS DIHNLRTETL HQQYELVRSH
//