ID A0A067H851_CITSI Unreviewed; 861 AA.
AC A0A067H851;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=GTP diphosphokinase {ECO:0000256|ARBA:ARBA00013251};
DE EC=2.7.6.5 {ECO:0000256|ARBA:ARBA00013251};
GN ORFNames=CISIN_1g002745mg {ECO:0000313|EMBL:KDO87140.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO87140.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO87140.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RelA/SpoT family.
CC {ECO:0000256|ARBA:ARBA00007476}.
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DR EMBL; KK784873; KDO87140.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067H851; -.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0008728; F:GTP diphosphokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd02116; ACT; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR CDD; cd01668; TGS_RSH; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR InterPro; IPR033655; TGS_RelA/SpoT.
DR PANTHER; PTHR43061; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR43061:SF1; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51880; TGS; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT DOMAIN 171..278
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT DOMAIN 537..600
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
FT COILED 305..336
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 861 AA; 96207 MW; F860BA7695F99D63 CRC64;
MASAASMSVS VECVNICKLP KGDGSGRYYD CSVLSCAWKA PRALTGFLAS TTHPAHSSSL
SLGPTGRRNR INSRCEAFDV GSWCTEGSDL VLLGKLPRSS LLHVACKRWR LCLSPSVSSD
AFKEDSPERL WEDLRPTISY LSPNELELVR RALMLAFEAH DGQKRRSGEP FIIHPVEVAR
ILGELELDWE SIAAGLLHDT VEDTNVVTFE RIEEEFGATV RRIVEGETKV SKLGKLKCKN
ENHSVQDVKA DDLRQMFLAM TEEVRVIIVK LADRLHNMRT LSHMPPHKQS ELENLSFMYT
NAEDYAKVKR RVADLYKEHE KELEEANKIL MKKIEDDQFL DLMTVKTEIR SVCKEPYSIY
KAVLKSRGSI NEVNQIAQLR IIIKPKPCSG VGPLCSPQQI CYHVLGLVHG IWTPIPRAMK
DYIATPKPNG YQSLHTTLIP FLYESMFRLE VQIRTEEMDL IAERGIAAHY SGRVFVTGLV
GHARPNGRSP RGKTVCLNNA NIALRISWLN AIREWQEEFV GNMTSREFVD TITRDLLGSR
VFVFTPRGEI KNLPKGATVV DYAYMIHTEI GNKMVAAKVN GNLVSPTHVL ANAEVVEIIT
YNALSSKSAF QRHKQWLEHA KTRSARHKIM KFLREQAALS ASEITADTVG DFVADSGEES
EVEDLSDGSK QDKPLWEKIL MNVVQMSSPV RNSKAVCSDD NASLWAPKVN GKHNKRVHYV
GSKAEGELSS QENSFAKMMH ANVPMYKEVL PGLESWQASK IATWHNLEGH SIQWFSVVCI
DRRGIMADVT TALATVGVTI CSCVAEIDRG RGIAVMLFHV EGNLESLVNA CSSVDLILGV
LGWSTGCSWP SSKGDWQFHE C
//
