ID A0A067KPB3_JATCU Unreviewed; 493 AA.
AC A0A067KPB3;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Legumain prodomain domain-containing protein {ECO:0000259|Pfam:PF20985};
GN ORFNames=JCGZ_07696 {ECO:0000313|EMBL:KDP34125.1};
OS Jatropha curcas (Barbados nut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae;
OC Jatropha.
OX NCBI_TaxID=180498 {ECO:0000313|EMBL:KDP34125.1, ECO:0000313|Proteomes:UP000027138};
RN [1] {ECO:0000313|EMBL:KDP34125.1, ECO:0000313|Proteomes:UP000027138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. GZQX0401 {ECO:0000313|Proteomes:UP000027138};
RC TISSUE=Young leaves {ECO:0000313|EMBL:KDP34125.1};
RX PubMed=24837971; DOI=10.1371/journal.pone.0097878;
RA Zhang L., Zhang C., Wu P., Chen Y., Li M., Jiang H., Wu G.;
RT "Global Analysis of Gene Expression Profiles in Physic Nut (Jatropha curcas
RT L.) Seedlings Exposed to Salt Stress.";
RL PLoS ONE 9:E97878-E97878(2014).
CC -!- SIMILARITY: Belongs to the peptidase C13 family.
CC {ECO:0000256|ARBA:ARBA00009941}.
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DR EMBL; KK914539; KDP34125.1; -; Genomic_DNA.
DR RefSeq; XP_012077326.1; XM_012221936.1.
DR AlphaFoldDB; A0A067KPB3; -.
DR STRING; 180498.A0A067KPB3; -.
DR MEROPS; C13.002; -.
DR GeneID; 105638176; -.
DR KEGG; jcu:105638176; -.
DR OrthoDB; 2951493at2759; -.
DR Proteomes; UP000027138; Unassembled WGS sequence.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IEA:InterPro.
DR CDD; cd21115; legumain_C; 1.
DR Gene3D; 1.10.132.130; -; 1.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR043577; AE.
DR InterPro; IPR048501; Legum_prodom.
DR InterPro; IPR046427; Legumain_prodom_sf.
DR InterPro; IPR001096; Peptidase_C13.
DR PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR12000:SF42; LEGUMAIN; 1.
DR Pfam; PF20985; Legum_prodom; 1.
DR Pfam; PF01650; Peptidase_C13; 1.
DR PIRSF; PIRSF500139; AE; 1.
DR PIRSF; PIRSF019663; Legumain; 1.
DR PRINTS; PR00776; HEMOGLOBNASE.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000027138};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..493
FT /note="Legumain prodomain domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001643885"
FT DOMAIN 380..476
FT /note="Legumain prodomain"
FT /evidence="ECO:0000259|Pfam:PF20985"
FT ACT_SITE 176
FT /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT ACT_SITE 218
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ SEQUENCE 493 AA; 54253 MW; 2B898476B3111B8E CRC64;
MTRLATGVIL LLLALCVVSS AGSRDIVGDV LRLPSEASRF FRPGGAHVAK EDDSTGTRWA
ILIAGSNGYW NYRHQADVCH AYQLLKKGGL KDENIIVFMY DDIAFNKENP RPGVIINNPY
GEDVYKGVPK DYTGEDVNVN NFFAAILGNK TAITGGSGKV VDSGPNDHIF IYYTDHGGPG
VLGMPTNPYL YANDLIDVLI KKHASGTYKS LVFYLEACES GSIFEGLLPE GLNIYATTAA
NAEESSWGTY CPGEYPSPPP EYETCLGDLY SVAWMEDSDV HNLQTETLRQ QYQLVKRRTA
NGNSAYGSHV MQYGDVGLSK DNLFLYMGTN PANENYTFVD ENSLRPPSKA VNQRDADLVH
FWDKYRKAPD GSTRKIQAQK QFVEAMSHRM HLDHSMKLIG KLLFGIGKGS EVLNAIRPAG
QPLVDDWVCL KTLVRTFETH CGSLSQYGMK HMRSLANLCN AGIREDQMAE ASAQACVSIP
SGPWSSLHKG FSA
//
