ID   A0A067KWD5_JATCU        Unreviewed;      1454 AA.
AC   A0A067KWD5;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN   ORFNames=JCGZ_01020 {ECO:0000313|EMBL:KDP39263.1};
OS   Jatropha curcas (Barbados nut).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae;
OC   Jatropha.
OX   NCBI_TaxID=180498 {ECO:0000313|EMBL:KDP39263.1, ECO:0000313|Proteomes:UP000027138};
RN   [1] {ECO:0000313|EMBL:KDP39263.1, ECO:0000313|Proteomes:UP000027138}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. GZQX0401 {ECO:0000313|Proteomes:UP000027138};
RC   TISSUE=Young leaves {ECO:0000313|EMBL:KDP39263.1};
RX   PubMed=24837971; DOI=10.1371/journal.pone.0097878;
RA   Zhang L., Zhang C., Wu P., Chen Y., Li M., Jiang H., Wu G.;
RT   "Global Analysis of Gene Expression Profiles in Physic Nut (Jatropha curcas
RT   L.) Seedlings Exposed to Salt Stress.";
RL   PLoS ONE 9:E97878-E97878(2014).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004287}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KK914353; KDP39263.1; -; Genomic_DNA.
DR   STRING; 180498.A0A067KWD5; -.
DR   Proteomes; UP000027138; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR   CDD; cd00171; Sec7; 1.
DR   Gene3D; 1.10.220.20; -; 1.
DR   Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR   InterPro; IPR023394; Sec7_C_sf.
DR   InterPro; IPR000904; Sec7_dom.
DR   InterPro; IPR035999; Sec7_dom_sf.
DR   PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR   PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   Pfam; PF01369; Sec7; 1.
DR   Pfam; PF12783; Sec7-like_HUS; 1.
DR   SMART; SM00222; Sec7; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF48425; Sec7 domain; 1.
DR   PROSITE; PS50190; SEC7; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027138}.
FT   DOMAIN          546..735
FT                   /note="SEC7"
FT                   /evidence="ECO:0000259|PROSITE:PS50190"
FT   REGION          910..942
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1423..1454
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        927..942
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1454 AA;  162198 MW;  710116519956F434 CRC64;
     MEEESVGCDS SYSNKATLAC MINAEVGAVL AVMRRNVRWG GRYVSGDDQL DHPLIQSLKA
     LRKQIFSCQH PWHTINPAVY LQPFLDVIRS DETSAPITGV ALSSVYKILT VDVIDQNTVN
     VKDAMHLVVD AVTSCRFEVT DPATEEVVLM KILQVLLACM KSKASATLSN QHVCTIVNTC
     FRIVHQAGTK GELLQRIARH TMHELVRCIF SLLPDVDNKE YAMVNGVSPT KQEIRGLDND
     YSFSSKQMEN GNNGSEFDGQ ASSVSFGSSA SSDLVATVME ENTIGVHSGK NALPHDLHLM
     TQPYGLPCMV EIFHFLCSLL NVVDHMGVGP RSNTIAFDED VPLFALGLIN SAIELGGPYI
     RHHPKLLSLI QDELFSNLMQ FGLSMSPLIL SMVCSIVLNL YHHLRAELKL QLEAFFSCVI
     LRLAQSRYGA SYQQQEVAME ALVDFCRQKT FMVEMYANLD CDITCGNVFE DLANLLSKSA
     FPVNCPLSAM HILALDGLIA VIQGMAEGID NGSVGSEQAP LNLEEYTPFW MEKCDNYSDP
     THWVPFVLQR KHIKRRLMIG ADHFNRDPKE GLKFLQGTHL LPNKLHPQSV ACFFRYTAGL
     DKNVIGDFLG NHDEFCVQVL HEFARTFDFQ GMNLDDALRL FLETFRLPGE SQKIQRVLEA
     FSERYYEQSP QILANKDAAL LLSYSLIMLN TDQHNVQVKK KMTEEDFVRN NRRINGGNDL
     PREFLSELYH SICKNEIRTT PEQGAGFPVM TSSRWISLIH NSKKTSPFIV YDSKAYLDRD
     MFAIMSGPAI AAISVVFDHA EHEDIYQTCI DGFLAVAKIS ACHHFEHVLD DLVVSLCKFT
     TLLDPSYPEE HVLAFGDDTK ARMATVALFT IANRYGDYIR TGWRNIMECI LRLHKLGLLP
     ACVASDVADE SETSADPGHG KPITNPLPSA HMQSTGAPKK SSGLMGRFSQ LLSLETEEPI
     SQPTEEELAA QRRTLETIQK CHVDSIFAES KFLQAESLEQ LAQALIWAAG GSQRGNSFPE
     DEDTAVFCLE LLIAITLNNR DRIVRLWQSV YEHIANIVQS TVMPCALVEK AVFGLLRICQ
     RLLPYKENLA DELLRSLQLV LKLDARVADA YCEQITVEVS RLVKANATHI RSLMGWRTIT
     SLLSITARHP EASEPGFDAL SFIMSDGVHL LPANYVLWVD AARQFAESRV AEAARSVHAL
     DLMTGSVDCL VRWSHEAKES LGEEEAAKLS QDIGEMWLRL VQGLRKVCLD QREEVRNHAL
     LSLQKCLTVV DGINLPPGLW LQCFDLVIFT LLDDLLENAQ GHTHKGYRNM DGTLIIAVKL
     LSKVFLRLLH DLSQLTTFSK LWLEVLSRME KYLKVKVRGR KSEKLHEAVP ELLKNTLLVM
     KTSGVLVQSS ASGGDSLWEL TWQHVNKIAP SLQSEVFPDQ ELEKLQPKNA ESGGGIMSDE
     TGSVPPNVSV ASGG
//