ID A0A067LEH0_JATCU Unreviewed; 768 AA.
AC A0A067LEH0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
GN ORFNames=JCGZ_00286 {ECO:0000313|EMBL:KDP42489.1};
OS Jatropha curcas (Barbados nut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Jatropheae;
OC Jatropha.
OX NCBI_TaxID=180498 {ECO:0000313|EMBL:KDP42489.1, ECO:0000313|Proteomes:UP000027138};
RN [1] {ECO:0000313|EMBL:KDP42489.1, ECO:0000313|Proteomes:UP000027138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. GZQX0401 {ECO:0000313|Proteomes:UP000027138};
RC TISSUE=Young leaves {ECO:0000313|EMBL:KDP42489.1};
RX PubMed=24837971; DOI=10.1371/journal.pone.0097878;
RA Zhang L., Zhang C., Wu P., Chen Y., Li M., Jiang H., Wu G.;
RT "Global Analysis of Gene Expression Profiles in Physic Nut (Jatropha curcas
RT L.) Seedlings Exposed to Salt Stress.";
RL PLoS ONE 9:E97878-E97878(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|ARBA:ARBA00009476, ECO:0000256|RuleBase:RU361221}.
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DR EMBL; KK914298; KDP42489.1; -; Genomic_DNA.
DR RefSeq; XP_012066731.1; XM_012211341.1.
DR AlphaFoldDB; A0A067LEH0; -.
DR STRING; 180498.A0A067LEH0; -.
DR GeneID; 105629706; -.
DR KEGG; jcu:105629706; -.
DR OrthoDB; 315083at2759; -.
DR Proteomes; UP000027138; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd04591; CBS_pair_voltage-gated_CLC_euk_bac; 1.
DR CDD; cd03685; ClC_6_like; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR002251; Cl_channel_pln.
DR PANTHER; PTHR11689:SF144; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR11689; CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR PRINTS; PR01120; CLCHANNELPLT.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Chloride {ECO:0000256|RuleBase:RU361221};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000027138};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 81..107
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 127..155
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 176..199
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 243..266
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 278..297
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 330..350
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 478..494
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 506..532
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 538..558
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT DOMAIN 702..766
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 768 AA; 84136 MW; 8597FE9092147EAE CRC64;
MDHTREGYDI EVEGSFAGME EDKEFNSMRE PLLRNRKNTT SQIAIVGANV CPIESLDYEI
FENELIKQDW RSRKKIEIFQ YIFLKWTLAL LIGLGTALVG LFNNLAVENI AGFKLLWTNS
LMLQDKYYQG FAAYAGSNLI LAIAAAALCA YVAPAAAGSG IPEVKAYLNG VDAPSILAPS
TLFIKIFGSI FGVAAGFVVG KEGPMVHTGA CIASLLGQGG SRKYHLTWRW LRYFKNDRDR
RDLVTCGAAA GVAAAFRAPV GGVLFALEEA ASWWRSALLW RTFFTTAVVA VVLRGFIEFC
RTGKCGLFGK GGLIMFDVNS GKAIYTTPDL LAVIFLGVIG GVLGSLYNYF VDKVLRTYSI
INEKGPLFKI MLVVIVSLLT SCCSYGLPWL APCIPCPPNL AERCPTGGRT GNYKNFQCPE
NHYNDLASLF FNTNDDAIRN LLTPGSEKRF QFSTLLVFFA AIYCLGIITY GIAVPSGLFI
PVILAGASYG RIVGKLLSPV SDLDVGLFSL LGAASFLGGT MRMTVSLCVI LLELTNNLLM
LPLMMLVLLI SKTVADAINK GVYDQILKMK GLPYMEAHAE PYMRHLVASD VVSGMLVTFS
GVEKVENILY ALKKTGHNGF PVIDEPPYTQ APELCGLVLR SHLLVLLKGK KFTKQREMTG
SGIRKSFRAH DFAKAGSGKG VKLEDLDITE EEMEMYVDLH PITNTSPYTV VETMSLAKAA
VLFRELGLRH LCVVPKTPGR PPVAGILTRH DFMPEHILGL YPHINPHK
//
