ID A0A067LXC8_9AGAM Unreviewed; 449 AA.
AC A0A067LXC8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Fatty acid desaturase domain-containing protein {ECO:0000259|Pfam:PF00487};
GN ORFNames=BOTBODRAFT_139354 {ECO:0000313|EMBL:KDQ08048.1};
OS Botryobasidium botryosum FD-172 SS1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Botryobasidiaceae; Botryobasidium.
OX NCBI_TaxID=930990 {ECO:0000313|EMBL:KDQ08048.1, ECO:0000313|Proteomes:UP000027195};
RN [1] {ECO:0000313|Proteomes:UP000027195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD-172 SS1 {ECO:0000313|Proteomes:UP000027195};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
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DR EMBL; KL198096; KDQ08048.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067LXC8; -.
DR STRING; 930990.A0A067LXC8; -.
DR HOGENOM; CLU_033094_0_0_1; -.
DR InParanoid; A0A067LXC8; -.
DR OrthoDB; 4215at2759; -.
DR Proteomes; UP000027195; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProt.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF35; OMEGA-3 FATTY ACID DESATURASE FAT-1; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027195};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..391
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 449 AA; 50034 MW; 056721175431E73D CRC64;
MSLVDNASLI QRDGDEDEIE KWTVPDLTVK DLLSVIPAHC WERSTLRSAS YVVWDFFLLG
LFLTATLHAE PYIAPAYIGF PHPALYSLAR FSLWSIYGFG AGLVGTGLWI IAHECGHGAF
SKSRTINHVV GWFLHSGLGV PYHSWRITHA KHHAYNGHLT LDQVFVPRTR SEHSASLPAF
DSAREDLDGT PSKVQKALQE ELREALHDAP LVAMAYCAVV LLFGWPWYLL ANVSGQRKHK
GASHFSPKAP FFAPTQSNQI LISDFGIIIW LGALISWAYL RGASEMIKIY LVPYLWVNHW
IVLITFLQHT DPIVPHYRAS SFTFPRGALS TLDRNLLGGD GFFGKITGWI GATTTHGISE
THVAHHVASK IPHYHAWEAS AALKVRLASA GYSFEGRPGT WGEIYRVWNA CKFVEDEGDV
VFYKDARGIA RRAAVFSDNN VSDSGVELQ
//
