ID   A0A067MJJ6_9AGAM        Unreviewed;       785 AA.
AC   A0A067MJJ6;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=BOTBODRAFT_158904 {ECO:0000313|EMBL:KDQ14875.1};
OS   Botryobasidium botryosum FD-172 SS1.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Cantharellales; Botryobasidiaceae; Botryobasidium.
OX   NCBI_TaxID=930990 {ECO:0000313|EMBL:KDQ14875.1, ECO:0000313|Proteomes:UP000027195};
RN   [1] {ECO:0000313|Proteomes:UP000027195}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FD-172 SS1 {ECO:0000313|Proteomes:UP000027195};
RX   PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA   Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA   Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA   LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA   Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA   Hibbett D.S., Grigoriev I.V.;
RT   "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT   white-rot/brown-rot paradigm for wood decay fungi.";
RL   Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; KL198035; KDQ14875.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067MJJ6; -.
DR   STRING; 930990.A0A067MJJ6; -.
DR   HOGENOM; CLU_004747_7_1_1; -.
DR   InParanoid; A0A067MJJ6; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000027195; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF182; CULLIN_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000027195};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          428..656
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          337..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        355..374
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   785 AA;  89521 MW;  38DECC56EA09AC55 CRC64;
     MSAIKLRKPK IKPPRKLGAD TAIEETWKLF SEAVREIFNH RASNLSYEEN YRYAYNLVLY
     KNGHVLYDGL RGLITENLDK LAKKDIVPAF PATGNADPVQ QSQEGERLLN ALRDVWEDHS
     QGMSRIRDLV KYMDKNYTVT AKVLPIWDAG VQLFLQRIIR SPAYNICSHI INCILTQIHI
     ERDGYTITRS SMKGCVDILL QIVDIDNGLS VYKTDLEPRV LQESKAFFEA ECERLLEVCD
     APEYLRRAEA HLASEAARTQ NYLSYDTHAP LQRIVEDYLL RAQFHTIMAM PSSGIDNMID
     TDKIEDLARL YRLFKIVPTE MPVLKKALKN SIAARGKTVN DASGEGEGGG EDEEEPQEVQ
     GKGKGKERAR PAKAGREQSA AVASKWVQDV LDLQDLFDRV LKLAFGNEVE LQTAINEAFE
     SFINLNPKAP EFISIFMDEN LKKGLKGKSD EEVEVLLDKT IGVFRFITEK DVFERYYKTH
     LAKRLLNGRS ISDDAERGML AKLKVECGFQ FTQKLEGMFH DMKLSAETMA AYKESVTRPS
     IDISVQVLTS TFWPMTHGVT PCTFSAEMNQ AITSFERYYL SRHSGRRLTW QAAMGSADVR
     ATFKARKHDL NVSTYALVVL LLFENVDEGG FLTYDEIKLA TSIEDVELRR TLQSLACAKF
     KVLKKHPPSR EVAQTDSFSF NNDFTAPLQR IKIGTVASRA ENDDQRKETM ERVDEERKHQ
     TDACIVRVMK DRKRMTHNDL INEATAQLAK RFQPNPAQIK KRIEALIERE YLDRGEDKKS
     YIYLA
//