ID A0A067N2A8_PLEOS Unreviewed; 640 AA.
AC A0A067N2A8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 28-JUN-2023, entry version 24.
DE RecName: Full=Manganese lipoxygenase {ECO:0000256|ARBA:ARBA00021175};
GN ORFNames=PLEOSDRAFT_1068582 {ECO:0000313|EMBL:KDQ22158.1};
OS Pleurotus ostreatus PC15.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotineae; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=1137138 {ECO:0000313|EMBL:KDQ22158.1, ECO:0000313|Proteomes:UP000027073};
RN [1] {ECO:0000313|Proteomes:UP000027073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC15 {ECO:0000313|Proteomes:UP000027073};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
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DR EMBL; KL198014; KDQ22158.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067N2A8; -.
DR SMR; A0A067N2A8; -.
DR STRING; 1137138.A0A067N2A8; -.
DR VEuPathDB; FungiDB:PLEOSDRAFT_1068582; -.
DR HOGENOM; CLU_009802_0_0_1; -.
DR InParanoid; A0A067N2A8; -.
DR OrthoDB; 1050333at2759; -.
DR Proteomes; UP000027073; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR GO; GO:0043651; P:linoleic acid metabolic process; IEA:UniProt.
DR GO; GO:0034440; P:lipid oxidation; IEA:InterPro.
DR Gene3D; 3.10.450.60; -; 1.
DR InterPro; IPR000907; LipOase.
DR InterPro; IPR013819; LipOase_C.
DR InterPro; IPR036226; LipOase_C_sf.
DR PANTHER; PTHR11771; LIPOXYGENASE; 1.
DR PANTHER; PTHR11771:SF153; LIPOXYGENASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00305; Lipoxygenase; 1.
DR SUPFAM; SSF48484; Lipoxigenase; 1.
DR PROSITE; PS51393; LIPOXYGENASE_3; 1.
PE 4: Predicted;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000027073}.
FT DOMAIN 162..640
FT /note="Lipoxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51393"
SQ SEQUENCE 640 AA; 71613 MW; 1DB6087F6CDF8934 CRC64;
MAPTMSLSRS ALKNVHLPYM VQHPEPTDYS TAMKQAVEGY DRARQMIAFL FDILDYESSV
PQKFTLEEKR EKYTWSRSGG FPPHLAIIPE AVAVPSYVIF SPVRLAQTLS ILSGIQSNDR
LAPGPEQNTM EKLTKWNAER HKNQGGIKNM YNEPNIGLRD DWYTDAVFAQ QFFTGTNPTT
ITLASDTWMK AFTEEAASQG KRDVISLFRS APPNSFYVQD FSDFRARMGA KPDEELCASS
DGGVKRYACA AVALFYLPPT GELHPLAIIP DYKGSMTASI TLFNKRVDPS DASVDQANDW
PWRYAKTCVL SADWVLHEMI IHLNNTHLVE EAVIVAVQRT LPDSHIVFRL LEPHWVVTLS
LNAQARSVLV PEVVVPVAGF SEPRILQFVG QAFTNFDWKA LYVPTDLESR GFPLDRLDDD
KFHNYAYARD IKDMWMALRK FVSSVLRDGK YYPDNSAVAA DAQIQDWCDE MRSEKGAGMK
KFPESISTLD DLIDMVTMCI HIAAPQHTAV NYLQQYYQTF VPNKPSALFS PLPTLLSQLE
SYTESDLMAA LPLGAKQDWL LMAQVPYLLS KEVEQDGNIV TYAGTASNNE DPIIAAAGKE
LSADLDILAG VFLKNSEKLD DQNTAYNVLA PDQLANAIVI
//
