ID A0A067N5U7_PLEOS Unreviewed; 369 AA.
AC A0A067N5U7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU367147};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU367147};
GN ORFNames=PLEOSDRAFT_1114413 {ECO:0000313|EMBL:KDQ23378.1};
OS Pleurotus ostreatus PC15.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotineae; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=1137138 {ECO:0000313|EMBL:KDQ23378.1, ECO:0000313|Proteomes:UP000027073};
RN [1] {ECO:0000313|Proteomes:UP000027073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC15 {ECO:0000313|Proteomes:UP000027073};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- FUNCTION: Esterase involved in the hydrolysis of xylan, a major
CC structural heterogeneous polysaccharide found in plant biomass
CC representing the second most abundant polysaccharide in the biosphere,
CC after cellulose. {ECO:0000256|RuleBase:RU367147}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Deacetylation of xylans and xylo-oligosaccharides.;
CC EC=3.1.1.72; Evidence={ECO:0000256|ARBA:ARBA00001691};
CC -!- PATHWAY: Glycan degradation; xylan degradation.
CC {ECO:0000256|ARBA:ARBA00004851}.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU367147}.
CC -!- SIMILARITY: Belongs to the carbohydrate esterase 1 (CE1) family. AxeA
CC subfamily. {ECO:0000256|ARBA:ARBA00007052}.
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DR EMBL; KL198013; KDQ23378.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067N5U7; -.
DR SMR; A0A067N5U7; -.
DR STRING; 1137138.A0A067N5U7; -.
DR VEuPathDB; FungiDB:PLEOSDRAFT_1114413; -.
DR HOGENOM; CLU_027551_1_1_1; -.
DR InParanoid; A0A067N5U7; -.
DR OrthoDB; 1740325at2759; -.
DR Proteomes; UP000027073; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0030248; F:cellulose binding; IEA:InterPro.
DR GO; GO:0045493; P:xylan catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000254; Cellulose-bd_dom_fun.
DR InterPro; IPR010126; Esterase_phb.
DR NCBIfam; TIGR01840; esterase_phb; 1.
DR PANTHER; PTHR43037:SF6; CARBOXYLIC ESTER HYDROLASE; 1.
DR PANTHER; PTHR43037; UNNAMED PRODUCT-RELATED; 1.
DR Pfam; PF00734; CBM_1; 1.
DR Pfam; PF10503; Esterase_PHB; 1.
DR SMART; SM00236; fCBD; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 2.
DR PROSITE; PS00562; CBM1_1; 1.
DR PROSITE; PS51164; CBM1_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU367147};
KW Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU367147};
KW Polysaccharide degradation {ECO:0000256|RuleBase:RU367147};
KW Reference proteome {ECO:0000313|Proteomes:UP000027073};
KW Secreted {ECO:0000256|RuleBase:RU367147};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487,
KW ECO:0000256|RuleBase:RU367147};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU367147}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|RuleBase:RU367147"
FT CHAIN 23..369
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU367147"
FT /id="PRO_5029032486"
FT DOMAIN 333..369
FT /note="CBM1"
FT /evidence="ECO:0000259|PROSITE:PS51164"
FT REGION 299..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..317
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 38920 MW; 309AFB3260DA7022 CRC64;
MSFSRLLSII AVLLVGPAGV LVNALSSTLQ QVSNFGPNPT GVQMFLYRPT KLASPPPLII
AMHYCTGTAQ AYFQGTSLAQ LADTHGFIVI YPDAPDSGGC WDVHSTATLT HDAGGDSLAI
ASMVRYAIAN YGVDASRVFA TGTSSGAMMT NVLMGAYPDL FKAGSLFSGV PYGCFAGSGM
WNSQCAQGQL IKTGQQWGDQ VRSGYPGFTG TRPKVQFWHG TADTTLYPQN FQEEIKQWTN
VFGVSETPTS TQTNNPLNGY TRTSYGPNVQ AILAQGVGHT VPEQENDVMI WFGLNNLTPG
TTNPPATTPP ATTPPATTPT QPTSTTIPSS PGGTAEHWGQ CGGQGWTGPT ACVSPFTCTA
LNAYYSQCL
//
