ID A0A067NAK8_PLEOS Unreviewed; 1040 AA.
AC A0A067NAK8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 28-JUN-2023, entry version 30.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=PLEOSDRAFT_1058771 {ECO:0000313|EMBL:KDQ24839.1};
OS Pleurotus ostreatus PC15.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotineae; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=1137138 {ECO:0000313|EMBL:KDQ24839.1, ECO:0000313|Proteomes:UP000027073};
RN [1] {ECO:0000313|Proteomes:UP000027073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC15 {ECO:0000313|Proteomes:UP000027073};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
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DR EMBL; KL198011; KDQ24839.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067NAK8; -.
DR STRING; 1137138.A0A067NAK8; -.
DR VEuPathDB; FungiDB:PLEOSDRAFT_1058771; -.
DR HOGENOM; CLU_004414_0_0_1; -.
DR InParanoid; A0A067NAK8; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000027073; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 2.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000027073};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 113..278
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 367..581
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
FT DOMAIN 589..1035
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 1040 AA; 116543 MW; FD4B845A840681B5 CRC64;
MEQETERVAQ AIAIAADPAQ VALHQEALYY LTTVQQNANN TWRLALSIFA DATPDGSRRY
SPQARFWALR LLEEFLDNRF EPLDDEAFQT LRQGFLTYIQ SEYVFGSAEA NASFLRNKFS
HTLTLFFLCT YIDQWPTFFA DIFALIRQDA SKFNRHVSLL FFHLVLEISG EVADQMIKAA
RTFNTQRHTR DGQVRDAVRE RDASQINEAV LTIIADGVER MSALREAGDS SRELGDVIEV
VDWGIRTFGS YVGWIDINLT VTPTTVPLLF TLLADPSLPI RLATSVALLR IVAKGLKEPS
DKLQLIKVLS LGQVIDALES KTRNQQIQRG SNTDEGEESY REALGKLLNI YGLELHKLID
DCSDQAIRTE ATQYLNQILP VLLRFMADEY DDTSSTIFTL LHTVLSSYKR SRKMSSEPIE
DSKRTFLVSL LNVILEKMKW EEDTDMDDPD DDDVAAFEGL RKELRSFMDG VLVIDQDLVT
EAVRTLALNT LAGYRNGVAV KWNDAELAIY LVYIFGEINK SGGKGRAAFC QAPSIDKTMR
KDVDYSEFPL TAHGEMLLSL VQSGISSYPH RAVVMQFFEA TASCPPSKGL HSQDSTVRSR
AFYLFYRFIK ENKTDFPSSV AVNLVEGIRD LLQIEVELPE IDEDSTKDIL TEALSTPSRF
DSQIYLFETV GVLCSLLKSP EEQSALLLSV AKPLLDELST NLQASTSSME PTAILRVHHI
IMALGNIAKG FPDFPSPVQP GHVLPPLEVL QQIAQAIIVC LEAMNVYKVV RDASRFAFAR
ILATAGPSVT QYIPPLMANL LNRFEPSELA DFMTFIGLLI HKLQRDMLGV LDELLGPLSS
HISSILAQPV SGTDDLVTRV DTKRAYLSLL NSIMASKLHS VFTSERNKAT FEPLLETVLR
EIEDLSDPSS QKTALTFFGR CVAVWGQPTG GPGENDAIPG FERFIYERLV PTAFSVLFKP
DYNIKDGQMF TVLHEIASFL QVVGKTRGTE AYEYFATVFL PGQNLPSQLA VEFATKLRDW
DGKAFRKYFA EFVRSSRPQA
//
